2008
DOI: 10.1089/bfm.2007.0035
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Milk Enzyme Activities and Subclinical Mastitis Among Women in Guinea-Bissau

Abstract: A positive association between the Na/K ratio and the breastmilk enzymes NAGase, LDH, AcP, and AP was found. Breastmilk enzymes have not previously been investigated in relation to SCM in women, and further research is warranted to highlight their specific role in the etiology of SCM.

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Cited by 14 publications
(11 citation statements)
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“…Our data show that the quantification of human cell-free DNA in breast milk may serve as a surrogate marker for SCM. Moreover, SCM has also been associated with increased production of proinflammatory mediators such as IL-8, RANTES, and lactoferrin [ 9 , 10 , 35 , 36 ] and in our study as well, high IL-8 levels strongly correlated with this condition.…”
Section: Discussionsupporting
confidence: 74%
“…Our data show that the quantification of human cell-free DNA in breast milk may serve as a surrogate marker for SCM. Moreover, SCM has also been associated with increased production of proinflammatory mediators such as IL-8, RANTES, and lactoferrin [ 9 , 10 , 35 , 36 ] and in our study as well, high IL-8 levels strongly correlated with this condition.…”
Section: Discussionsupporting
confidence: 74%
“…SCM was defined by a Na/K ratio in breast milk > 1, as described elsewhere [ 17 , 18 , 45 , 46 ]. Maternal breast health problems (such as mastitis, engorgement, cracked/bleeding nipple, blocked duct, breast thrush, breast/nipple oozing pus and abscess [ 24 ]) were considered if they occurred during the week before the sample collection date because mastitis markers are normalized within 1 week after symptom resolution [ 13 ].…”
Section: Methodsmentioning
confidence: 99%
“…Concentrations below the lower limit of quantification were assigned half the value of the lower limit, as described elsewhere [ 39 , 48 ]. Conversely, concentrations above the upper limit of quantification were assigned the value of the upper limit [ 17 ]. Immunologic factors for which 50% or more of the samples in a group were below the lower limit of quantification of the test weren’t quantitatively analyzed.…”
Section: Methodsmentioning
confidence: 99%
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