Minimal increase in serum interleukin-6 levels during laparoscopic cholecystectomy

Ueo, Hiroaki; Honda, Masaaki; Adachi, Masashi; Inoue, Hiroshi; Nakashima, Hiroaki; Arinaga, Shinya; Akiyoshi, Tsuyoshi

doi:10.1016/s0002-9610(05)80166-7

Cited by 64 publications

(29 citation statements)

References 5 publications

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“…In human medicine, many comparative studies between laparoscopic surgery and open surgery have been reported [10,15,18]. The increases in the serum interleukin-6 and C-reactive protein levels during laparoscopic surgery were found to be significantly smaller than those during open surgery [10,18]. These results demonstrate that aspects of the metabolic and acute-phase responses are attenuated following laparoscopic surgery, consistent with a reduction in tissue trauma [10].…”

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confidence: 72%

“…In the present cases, total skin incision length was only 6 cm, and three out of four incisions were only 1 cm. In human medicine, many comparative studies between laparoscopic surgery and open surgery have been reported [10,15,18]. The increases in the serum interleukin-6 and C-reactive protein levels during laparoscopic surgery were found to be significantly smaller than those during open surgery [10,18].…”

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confidence: 99%

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Successful Laparoscopy Assisted Ovariohysterectomy in Two Dogs with Pyometra.

Minami

Okamoto

Eguchi³

et al. 1997

J. Vet. Med. Sci.

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ABSTRACT. Two dogs with pyometra were treated by laparoscopy assisted ovariohysterectomy. Hemostasis of the mesovarium was achieved with an ultrasonic scalpel and hemoclips. Both ovaries and the uterus were exposed via a 10-mm caudal port that was enlarged to 3 cm and the uterine cervix was excised after ligation of the uterine arteries. These cases were the first report on ovariohysterectomy for pyometra by laparoscopy assisted surgery in the veterinary field. -KEY WORDS: canine, laparoscopic surgery, pyometra.

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confidence: 72%

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confidence: 99%

Successful Laparoscopy Assisted Ovariohysterectomy in Two Dogs with Pyometra.

Minami

Okamoto

Eguchi³

et al. 1997

J. Vet. Med. Sci.

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“…In one study, CRP and IL-6 levels were evaluated in venous blood samples 12 hours after OA and LA in children, and it was identified that CRP levels significantly decreased in the LA group as compared to OA group (28). The abdominal organs do not come into contact with atmospheric air in LA, therefore the heat loss is less and the acute phase response is minimal (29 th postoperative days and reported that CRP levels were significantly lower in the LA group as compared to the OA group. In our study, the postoperative decrease in WBC count was significant in the LA group, while the postoperative decrease in WBC count did not reach statistical significance in the OA group.…”

Section: Discussionmentioning

confidence: 99%

Should appendectomy be performed laparoscopically? Clinical prospective randomized trial

Mantoğlu¹,

Karıp²,

Mestan³

et al. 2015

UCD

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Objective: Laparoscopic appendectomy (LA) has been described in 1983, and its superiority over open appendectomy (OA) is still being debated. Currently, there is no agreement on the advantages of LA. Postoperative pain is reported to be lower along with a faster return to normal activities in LA. However, some studies do not support these findings. In our study, we aimed to compare the outcomes and cost effectiveness of LA and OA. Material and Methods:Patients were prospectively randomized into LA (31 patients) and OA (32 patients) groups. Demographic data, pre-and postoperative C-reactive protein (CRP) levels, white blood cell (WBC) count, duration of surgery and hospitalization, complications, and pain scores (VAS) were recorded. Cost was calculated for both groups. Return to normal activities was evaluated by phone calls at the first and second week and 1 month after surgery.Results: There was a significant postoperative decrease in WBC count in the LA group (p<0.01). There were no differences between LA and OA groups in terms of postoperative CRP levels (p>0.05). The rates of wound infection and abscess were similar (p>0.05), while post-operative pain and time to return to normal activities were higher in the OA group (p<0.01). There was a positive correlation between BMI and operative time in the LA group (p<0.01), while BMI and operative time did not show a correlation in the OA group (p>0,05). The average cost in the LA and OA groups were 1960.5±339.05 and 687.115±159.5 TL, respectively. Conclusion:LA is an effective method in the treatment of acute appendicitis due to less pain and faster recovery. LA can be the choice of treatment in acute appendicitis, with utilization of re-useable and cheaper vascular sealing devices.

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“…When the body is subjected to surgical stress, levels of inflammatory cytokines such as TNF-␣, IL-1␤, IL-6 and IL-8 are known to increase, while at the same time, levels of anti-inflammatory cytokines such as IL-4 and IL-10 are also elevated. From the perspective of measurement sensitivity, IL-6 in the plasma can be easily detected after surgery, and is frequently used as a SIRS marker 3,7,11,[15][16][17][21][22][23]27,31) . Studies have shown that plasma levels of IL-6 are significantly higher in patients with postoperative SIRS 7,20,22,31) , remain high in deceased patients with SIRS 7,20) , and closely reflect degree of surgical stress 4) .…”

Section: Changes In Cytokinesmentioning

confidence: 99%

Systemic Inflammatory Response Syndrome and postoperative complications after orthognathic surgery

Kasahara

Yamamura²,

Sugahara³

et al. 2014

Journal of Oral and Maxillofacial Surgery

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Symptoms of Systemic Inflammatory Response Syndrome (SIRS) presenting immediately after surgery have lately been regarded as potential warnings of impending postoperative complications and multiple organ failure. Reports discussing the relationship between operative stress and SIRS are found in the field of digestive surgery, but not in that of oral surgery. Sixty-five patients with jaw deformity who had undergone maxillary and mandibular orthognathic surgery (Le Fort I osteotomy and sagittal splitting ramus osteotomy) between September 2003 and October 2006 were involved in this study. A search based on the SIRS diagnostic criteria resulted in assignment of 33 cases to the SIRS group and 32 cases to the non-SIRS group. Postoperative complications occurred in 27.3% of the SIRS group and 0.0% of the non-SIRS group (pϽ0.01). In four cases, a postoperative fluctuation in IL-6 level evaluated. These results suggest the importance of careful management of postoperative SIRS patients in preventing complications.

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Minimal increase in serum interleukin-6 levels during laparoscopic cholecystectomy

Cited by 64 publications

References 5 publications

Successful Laparoscopy Assisted Ovariohysterectomy in Two Dogs with Pyometra.

Successful Laparoscopy Assisted Ovariohysterectomy in Two Dogs with Pyometra.

Should appendectomy be performed laparoscopically? Clinical prospective randomized trial

Systemic Inflammatory Response Syndrome and postoperative complications after orthognathic surgery

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