Minimum 6-year outcomes for interstitial cystitis treated with sacral neuromodulation

Marinkovic, Serge P.; Gillen, Lisa M.; Marinkovic, Christina M.

doi:10.1007/s00192-010-1235-9

Cited by 63 publications

(50 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No RCTs have been completed to assess the effect of SNM on symptoms of IC/BPS. However, multiple observational studies have been reported, [188][189][190][191][192][193][194][195] including long-term followup of 86 ± 9.8 months. 191 All studies include patients refractory to multiple IC/BPS treatment options.…”

Section: Sacral Neuromodulation (Snm) (Option Grade C)mentioning

confidence: 99%

See 1 more Smart Citation

CUA guideline: Diagnosis and treatment of interstitial cystitis/ bladder pain syndrome

Cox

Golda

Nadeau

et al. 2016

CUAJ

115

121

View full text Add to dashboard Cite

MethodologyThe following guidelines were based on MEDLINE and PUBMED searches of English language literature, in addition to consensus conference proceedings. Levels of evidence and grades of recommendation were assigned for each investigation and treatment, as per the modified Oxford Centre for Evidence-Based Medicine grading system. Where the literature was inconsistent or scarce, a consensus expert opinion was generated to provide treatment guidelines.

show abstract

Section: Sacral Neuromodulation (Snm) (Option Grade C)mentioning

confidence: 99%

“…There is a surgical revision rate of 27-50%. 189,191 Guideline: Based on consistent Level 3 evidence, SNM may be offered as an option for the treatment of IC/BPS to patients who have symptoms refractory to multiple other treatments. Therapy is costly and not widely available at all centres.…”

Section: Sacral Neuromodulation (Snm) (Option Grade C)mentioning

confidence: 99%

CUA guideline: Diagnosis and treatment of interstitial cystitis/ bladder pain syndrome

Cox

Golda

Nadeau

et al. 2016

CUAJ

115

121

View full text Add to dashboard Cite

show abstract

“…Frequently, it resolves or reduces associated CPPS. Marinkovic et al [49] evaluated patients after implantation with InterStim (Medtronic, Fridley, MN) over a minimum 6-year follow-up and determined that SNS provides adequate improvement for the symptoms of refractory interstitial cystitis. Van Wunnik et al [50] used SNS for the treatment of chronic functional anorectal pain.…”

Section: Neurostimulationmentioning

confidence: 98%

Pelvic Floor Therapies in Chronic Pelvic Pain Syndrome

Doggweiler

Stewart

2011

Curr Urol Rep

View full text Add to dashboard Cite

Chronic pelvic pain syndrome is a poorly understood clinical entity associated with urinary symptoms, pelvic floor dysfunction, and multisystem disorders. Treatment of pelvic floor dysfunction is difficult and often frustrating for the patient as well as for the involved physician. The purpose of this review is to update clinicians on the latest research for the treatment of pelvic floor dysfunction in relation to chronic pelvic pain syndrome.

show abstract

“…Mean voided volume increased from 111 to 264 ml and pain decreased from 5.8 to 1.6 on a 0 to 10 visual analog pain scale. Another study with a follow-up of a mean of 86 months reported a 64% reduction of pain in 30 patients who underwent SNM [40]. SNM might be effective for treating neurogenic bladder patients, but, as in BPS, the level of evidence is low [41].…”

Section: Nonobstructive Chronic Underactive Bladdermentioning

confidence: 99%

Sacral Neuromodulation for the Treatment of Urinary Bladder Dysfunction: Mechanism of Action and Future Directions

Blok

2017

Bioelectron. Med.

View full text Add to dashboard Cite

Symptoms of overactive bladder affect a large portion of the world population, especially the elderly. Sacral neuromodulation (SNM) is an effective third-line therapy in patients with overactive bladder. The working mechanism of SNM can be explained by the neural connections of the lower urinary tract. It is proposed that SNM does not work directly on the central components of the micturition reflex, but on cortical and subcortical areas, which in turn inhibits the micturition reflex components in the caudal brainstem. The clinical use and outcomes of SNM are described for several forms of bladder dysfunction. Furthermore, some recent new developments in SNM are discussed, such as expanded indications, more effective use of existing nonrechargeable neuromodulators and the introduction of a rechargeable device. Conservative treatment of overactive bladder (OAB) with or without urinary incontinence consists of pelvic floor exercises, medication and lifestyle intervention, including fluid restriction and timely voiding. If these conservative interventions fail, it is possible to offer electrical stimulation therapies, such as sacral neuromodulation (SNM). In patients suffering from urinary urgency, frequency and urgency incontinence, electrical stimulation of the sacral nerve significantly reduces urinary symptoms and improves patient quality of life. SNM is also used effectively for other forms of bladder dysfunction, such as underactive bladder and bladder pain syndrome (BPS). The increased use of minimally invasive SNM has decreased the need for more open surgical procedures such as ileocystoplasty and urinary diversion. SNM uses an implanted electrode to the third or fourth sacral spinal nerve to deliver a nonpainful electrical stimulus. The brain of the patient perceives this stimulus and, in turn, effectively restores bladder function and alleviates the patients' symptoms. Due to the system-oriented, and not organ-oriented, approach, SNM not only treats urinary disorders, but may also have a beneficial effect on bowel and sexual dysfunction as well as on pelvic pain. Normal control of the lower urinary tractIn order to understand the role of the brain in the control of the urinary bladder and its sphincter, one can make a distinction between structures and axonal tracts in the caudal brainstem and spinal cord, which are intrinsic part of the micturition and continence reflex, and structures and pathways, located in the forebrain and mesencephalon, which modulate these micturition and continence areas. Most of the clinical therapies aimed at functional bladder disorders are not specifically targeted to the micturition reflex areas, but influence cortical and subcortical brain areas, which, in turn, modulate the micturition reflex components. Examples of such therapies are pelvic floor physiotherapy, biofeedback, transcutaneous electrical nerve stimulation, posterior tibial nerve stimulation and SNM. Currently, there is no effective behavioral, chemical or electrical treatment which works directly and specifica...

show abstract

Minimum 6-year outcomes for interstitial cystitis treated with sacral neuromodulation

Abstract: With a minimum 6-year follow-up we determined that sacral neuromodulation provides adequate improvement for the symptoms of recalcitrant interstitial cystitis.

Cited by 63 publications

References 19 publications

CUA guideline: Diagnosis and treatment of interstitial cystitis/ bladder pain syndrome

CUA guideline: Diagnosis and treatment of interstitial cystitis/ bladder pain syndrome

Pelvic Floor Therapies in Chronic Pelvic Pain Syndrome

Sacral Neuromodulation for the Treatment of Urinary Bladder Dysfunction: Mechanism of Action and Future Directions

Contact Info

Product

Resources

About