Misconceptions and Facts About Mitral Regurgitation

Background: The arrival of transcatheter mitral valve therapies has provided feasible and safe alternatives to medical and surgical treatments for mitral regurgitation. The aim of this study is to estimate the relative efficacy and safety of different transcatheter mitral valve therapies for mitral regurgitation patients through network meta-analysis. Methods: A systematic search will be performed using PubMed, EMBASE, the Cochrane Library, Web of Science, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure to include random controlled trials and nonrandom controlled trials comparing the efficacy and safety of different transcatheter mitral valve techniques. The risk of bias for the included nonrandom controlled studies will be evaluated according to Risk of Bias in Non-randomized Studies - of Interventions. For random controlled trials, we will use Cochrane Handbook version 5.1.0 as the risk of bias tool. A Bayesian network meta-analysis will be conducted using R-4.0.3 software. Grading of recommendations assessment, development, and evaluation will be used to assess the quality of evidence. Results: The results of this network meta-analysis will be submitted to a peer-reviewed journal for publication. Conclusion: This study will provide broad evidence of efficacy and safety of different transcatheter mitral valve therapies for treatment of mitral regurgitation and provide suggestions for clinical practice and future research. Protocol registration number: INPLASY2020110034.

show abstract

Mitral Regurgitation Severity Analysis Based on Features and Optimal HE (OHE) with Quantification using PISA Method

Khayum¹,

Babu²

2017

Journal of Intelligent Systems

View full text Add to dashboard Cite

Heart disease is the foremost reason for death and also the main source of incapability in the developed nations. Mitral regurgitation (MR) is a typical heart disease that does not bring about manifestations until its end position. In view of the hidden etiologies of heart distress, functional MR can be partitioned into two subgroups, ischemic and no ischemic MR. A procedure is progressed for jet area separation and quantification in MR evaluation in arithmetical expressions. Thus, a strategy that depends on echocardiography recordings, image processing methods, and artificial intelligence could be useful for clinicians, particularly in marginal cases. In this research paper, MR segmentation is analyzed by the optimal histogram equalization (OHE) system used to segment the jet area. For a better execution of the work, threshold in HE was improved with the help of the krill herd optimization (KHO) strategy. With the MR quantification procedure, this segmented jet area was supported by the proximal isovelocity surface area (PISA); in this procedure, a few parameters in the segmentation were evaluated. From the results, this proposed methodology accomplishes better accuracy in the segmented and quantification method in contrast with the existing examination.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Misconceptions and Facts About Mitral Regurgitation

Cited by 3 publications

References 24 publications

Misconceptions and Facts About Aortic Stenosis

Misconceptions and Facts About Aortic Stenosis

Comparison of different transcatheter interventions for treatment of mitral regurgitation

Mitral Regurgitation Severity Analysis Based on Features and Optimal HE (OHE) with Quantification using PISA Method

Contact Info

Product

Resources

About