1975
DOI: 10.1099/00221287-88-1-20
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Missense Suppression in Coprinus lagopus Associated with a Chromosome Duplication

Abstract: SUMMARYAmongst some 70 recessive suppressors of a met-I mutation in Coprinus lagopus, one unstable suppressor was identified. The unstable suppressor, designated sup-6+, could be maintained on minimal medium, but was lost within 24 h on minimal medium containing more than 1.7 p.p.m. DL-methionine or 0.75 p.p.m. Lmethionine. Isolation of hyphal tips from the monokaryotic strain carrying sup-6+ yielded three types of colony: the unstable parental type, the stable met-r auxotroph and a stable prototroph which was… Show more

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