Mission-Aware Differences in Cyberbiosecurity and Biocybersecurity Policies: Prevention, Detection, and Elimination

Organoids, Biocybersecurity, and Cyberbiosecurity—A Light Exploration

“…Key terms that have emerged in the course of this work include "organoids", "biocomputing", and "cyberbiosecurity" (CBS)/"biocybersecurity" (BCS). BCS and CBS refer to different mission orientations and attack origins [45,46]. BCS focuses on attacks originating from biological systems or using them as an interlock.…”

“…BCS focuses on attacks originating from biological systems or using them as an interlock. CBS refers to attacks originating in hardware and computer systems with a focus on biological or biology-centric systems, though a useful primer is presented in past literature [45,46]. BCS is an emerging interdisciplinary field combining cybersecurity, bioinformatics, and biological research elements.…”

“…The digitization of biological data requires a nuanced understanding of biological systems and digital security, creating a unique interdisciplinary field. The primary focus is safeguarding sensitive biological data, which has become increasingly vulnerable in the digital age [45][46][47][48]. This vulnerability is not just limited to hacking and unauthorized access but also affects data manipulation, poisoning, integrity, and more.…”

“…As biological research continues to become more data-intensive, the importance of CBS becomes ever more critical [49,50]. Overall, the field aims to establish protective protocols by drawing attention to issues such as data breaches in biomedicine, the misuse of biological data, and the vulnerabilities of biotechnological devices to hacking, where biology is a core interlock as opposed to just any matter where cybersecurity and biosecurity converge [46,47]. For the purpose of this article, the relevance of CBS and BCS exists due to their ability to be used as an interlock in future computing systems and for the awareness for programs to be in place to protect these biological systems, data, and technologies.…”

“…Several security-facing possibilities may exist, although in speculation. We may see organoids providing a closer environment for testing biocybersecurity protocols via biocomputing applications compared to in silico models, for applications such as developing biological sensors or detectors based on an organ-like context [1,17,26,[45][46][47][48][49][50][51][52][53][54][55][56]. STEM may eventually see organoids offer a more nuanced platform for studying how biological systems interact with cyber systems, enhancing our understanding of potential vulnerabilities and solutions in biosecurity.…”