2015
DOI: 10.1002/jmv.24197
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Mitochondrial haplogroups and control region polymorphisms in Kaposi's sarcoma patients

Abstract: Inflammation and reactive oxygen species (ROS) production have recently considered as key mechanisms in the pathogenesis of Kaposi's sarcoma (KS). Since mitochondria are the major source of ROS production, this organelle may play a main role in KS development. However, there are no studies on mtDNA variations and haplogroups in this area. The focus of this study was to investigate the mtDNA variants and haplogroups in KS patients and their relationship to tumor development. To address this, we have genotyped m… Show more

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