In this paper we introduce mixed coloured permutation, permutations with certain coloured cycles, and study the enumerative properties of these combinatorial objects. We derive the generating function, closed forms, recursions and combinatorial identities for the counting sequence, mixed Stirling numbers of the first kind. In this comprehensive study we consider further the conditions on the length of the cycles, r-mixed Stirling numbers and the connection to Bell polynomials.2010 Mathematics Subject Classification. 05A18, 11B73.