2024
DOI: 10.1101/2024.07.16.603832
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

MLL4 regulates postnatal palate growth and midpalatal suture development

Jung-Mi Lee,
Hunmin Jung,
Bruno de Paula Machado Pasqua
et al.

Abstract: MLL4, also known as KMT2D, is a histone methyltransferase that acts as an important epigenetic regulator during various organogenesis programs. Mutations in the MLL4 gene are the major cause for Kabuki syndrome, a human developmental disorder that involves craniofacial birth defects, including anomalies in the palate. The purpose of this study was to investigate the role of Mll4 and the underlying mechanisms in the development and growth of the palate. We generated a novel conditional knockout (cKO) mouse mode… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 56 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?