Mo1022 PEG-3350 for Colon Preparation in Children: Head to Head Comparison Between 2 and 4 Days Protocols

Elitsur, Rotem; Butcher, Lisa; Lund, Vicki A.; Elitsur, Yoram

doi:10.1016/s0016-5085(12)62204-5

Cited by 2 publications

(5 citation statements)

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“…Vomiting was noted in 3 (3.3 %) patients. Similar results were noted in the previous study, showing abdominal cramps in 32 % and vomiting 2.5 % 11 . No patients failed to complete the colon cleansing protocol due to side effects.…”

Section: Resultssupporting

confidence: 92%

“…In that study, other colonoscopy landmarks were measured including: terminal ileum (TI) intubation rate and clinical side effects (vomiting, abdominal pain). Our results showed an adequate preparation rate of 73.6 % after the 2-day protocol 11 .…”

Section: Introductionsupporting

confidence: 52%

“…We believe that a successful research protocol should be used routinely by the authors in their normal clinical practices to show the suitability of their research protocol for clinical practice. This supposition is supported by overall failure rates for different cleansing protocols in children, which were estimated in different studies between 21 % and 34 % 7 8 9 10 11 . Whether the high rate of unprepared colons reflects the failure of a previously published research protocol or new protocol used by the respected authors is not known.…”

Section: Introductionmentioning

confidence: 87%

“…In this retrospective study, the colon cleansing protocol included PEG-3350 at a dose of 2 g/kg/day plus Dulcolax (Bisacodyl, Boehringer Ingelheim, Texas, United States) 5 mg/day as previously described 11 . Patients were instructed to mix 8 oz of liquid for each 17 g of PEG 3350 consumed, provided that the liquid was not red.…”

Section: Methodsmentioning

confidence: 99%

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Colon cleansing protocol in children: research conditions vs. clinical practice

2018

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Background and study aims Colon preparation rates are the limiting factor for a successful diagnostic colonoscopy in children. Different colon cleansing protocols have been published for use in children. Unfortunately, the applicability of those published research protocols has not been formally evaluated in routine clinical practice. We investigated the success rate of our previously published colon cleansing protocol as utilized in our clinical practice. Patients and methods This was a retrospective study. In the clinical practice, the colon cleansing protocol included PEG-3350 at a dose of 2 g/kg/day plus Dulcolax (Bisacodyl, Boehringer Ingelheim, TX USA) 5 mg/day for 2 days. Adequate colon preparation was graded between 1 – 5, as previously described, and grade ≥ 4.0 was considered an adequate preparation. Patients were instructed to complete a questionnaire that included PEG-3350 dose, number of stools per day, consistency of each stool, and side effects (vomiting, abdominal pain). Clinical and endoscopic results were compared between the protocol under research conditions and routine practice. Results The success rate of the colon preparation in our clinical practice was similar to the results observed under our research protocol (75 % vs. 73.6 %). Moreover, the total number of stools, stool consistency, and the intubation rate of the terminal ileum were also similar. We concluded, that in our experience, the colon cleansing protocol used under research conditions was effective and appropriate for use in routine clinical practice. Conclusion We recommend testing each new protocol under the routine conditions of clinical practice to confirm its applicability for general practitioners.

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Section: Resultssupporting

confidence: 92%

Section: Introductionsupporting

confidence: 52%

Section: Introductionmentioning

confidence: 87%

Section: Methodsmentioning

confidence: 99%

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Colon cleansing protocol in children: research conditions vs. clinical practice

2018

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“…), are usually blocked by the limitation of human consumption, and is the wrong direction to follow. We recently completed the first headto-head comparison between 2 PEG 3350-based protocols (5,6) to find the superior protocol and to examine protocol reproducibility (7). In the quest for the criterion standard, we need to concentrate on the simplicity, acceptability, reliability of grading, and, most important, the rate of successful preparation.…”

Section: Colon Preparation For Children: Thementioning

confidence: 99%

Colon Preparation for Children

Elitsur

2013

J. pediatr. gastroenterol. nutr.

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Mo1022 PEG-3350 for Colon Preparation in Children: Head to Head Comparison Between 2 and 4 Days Protocols

Cited by 2 publications

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Colon cleansing protocol in children: research conditions vs. clinical practice

Colon cleansing protocol in children: research conditions vs. clinical practice

Colon Preparation for Children

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