MO107: Association of Renal Function with Cardio Metabolic Risk Factors in Elderly Population

Abstract

BACKGROUND AND AIMS Elderly population is a vulnerable group, and cardiometabolic risk factors are highly prevalent among them. This situation complicates when the renal function becomes impaired. The aim of this study was to evaluate the association of renal function with cardiometabolic risk factors among the elderly subjects. METHOD This cross-sectional study was conducted among a group of elderly population (>60 years) living in three different elderly residential complexes. Written informed consent was taken from all. Study population underwent detail history taking, physical examination and relevant investigations. Renal function (eGFR) was estimated by CKD-EPIcr formula. Renal (eGFR, Ur ACR), cardiac (blood pressure, BMI, waist/hip ratio) and metabolic risk factors (lipids, albumin, uric acid, HbA1c) were evaluated. All information was recorded in separate case record form. Collected data were checked for errors and then analysed using the statistical software SPSS 16. RESULTS Around 145 subjects were included. About 42% were from 60–65 years of age, 37% from 66–70 years and rest > 70 years. Mean age was 68 ± 5 years with male 52%. Mean eGFR was 71 ± 2 and in male versus female it was 75 ± 22 versus 66 ± 24 mL/min/1.73 m2 (P < .032) . In 20% elderly eGFR was observed < 60 mL/min/1.73 m2. Prevalence of DM, HTN and obesity was 33%, 46% and 9%, respectively. Age (69 ± 5 and 67 ± 5 years, P < .012), waist/hip ratio (1.01 ± 0.16 and 0.97 ± 0.07, P < .04), serum creatinine (1.6 ± 0.4 and 0.9 ± 0.2 mg/dL, P < .001), urinary ACR (320 ± 565 and 82 ± 213 mg/g, P < .001) were significantly altered among patients with impaired renal function (<60 versus >60 mL/min). CONCLUSION This study showed that various cardiometabolic risk factors among elderly patients are significantly higher in those with impaired renal function.

Association between Clustering of Cardiometabolic Risk Factors and Chronic Kidney Disease: Findings from the China Health and Retirement Longitudinal Study

“…Similarly, research by Kibria and Zheng identi ed a strong association between cardiovascular disease risk factors and declining kidney function, particularly in older adults. These studies also observed a greater burden of cardiometabolic challenges in individuals with compromised renal health, suggesting a bi-directional relationship [25,26]. Notably, Leis et al found that the risk of postoperative acute kidney injury (AKI) differed based on speci c cardiometabolic phenotypes [4].…”