Model for predicting risk of developing drug-induced liver injury during remdesivir therapy: observational prospective open case-control study
Yu. V. Shevchuk,
A. V. Kryukov,
I. I. Temirbulatov
et al.
Abstract:Remdesivir is a drug widely used for the etiotropic treatment of COVID-19. According to a number of studies, the incidence of adverse reactions during remdesivir therapy reaches 66%, with the most common is an increase in liver function tests.The aim of the work was to study the influence of clinical, demographic and pharmacogenetic factors on the development of drug-induced liver damage during remdesivir therapy in COVID-19 patients.Materials and methods. The study comprised 100 hospitalized patients treated … Show more
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