Coarse–fine composite mechatronic systems face numerous challenges due to the structural complexity and diversification of multi-gimbals. The core goal of this manuscript is to address the issue of the coarse-fine composite mechatronic system stability of a UAV (unmanned aerial vehicle) multi-gimbal electro-optical pod using USM-VCM (ultrasonic motor and voice coil motor) mechatronic design, Euler dynamics modeling, and stability DOB (disturbance observer) control. In response to this problem, a Hall effect electromagnetic circuit and USM-VCM drive acquisition circuit are designed. A Euler dynamics model in the Cartesian coordinate system is built to derive the kinematics coupling compensation matrix and mechanical parameter optimization method between the gimbals. Finally, the model is substituted into the DOB suppression control, which can monitor and compensate the motion coupling between the coarse–fine composite mechatronic systems in real time. Results show that the disturbance suppression impact of the DOB method with the Euler optimization model and USM-VCM mechatronic design is increased by up to 90% compared to the PID (proportion integration differentiation) method and 20% better than the traditional DOB method.