Modeling approaches to optimize the recovery of polyphenols using ultrasound-assisted extraction

Gullón, Patricia; Gullón, Beatriz; Astray, Gonzalo; Costa, Patrícia; Lorenzo, José M.

doi:10.1016/b978-0-12-818275-8.00004-0

Cited by 5 publications

(2 citation statements)

References 48 publications

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“…The first phase indicates for the washing process that the compounds are dissolved in the solvent, while the second phase is calculated as a slow phase due to mass transfer limitations, unlike the first phase. In the second phase, which is considered as a diffusion process, the dissolved substances from the cells of the inner wall are distributed in the solvent [16,19]. Experimental data are generally processed and analyzed using physical kinetic models to investigate the kinetics of the extraction process and to describe the mechanisms that drive it.…”

Section: Introductionmentioning

confidence: 99%

"Kinetic Modelling of Ultrasound-Assisted Extraction of Bioactive Compounds from Helichrysum Arenarium"

Bajrami¹

2023

BJSTR

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In this paper, the kinetics of bioactive components from Helichrysum arenarium under ultrasounds action was investigated. The aim of this study was to do model validation by plotting experimental data and to be seen if the correlation coefficient fits the experimental data. The process takes place in two stages: a fast one in the first stage 0-75 min, followed by slow phase from 75-180 min, in the second phase the equilibrium concentration was approached after 80 min. The modelling of kinetics in two phases (fast and slow) is done through the mathematical interpretations of the kinetically controlled process and the diffusion controlled process, also with a separate analysis of the two phases separately and finally they are combined into one process. From the results it can be seen that in the first stage the correlation coefficient (R2) has values above 0.9, which indicates that the selected models perfectly fit the experimental data, while for the second stage, the correlation coefficients vary below 0.9 however, these values (above 0.8) show that this model is accurate enough to determine the kinetics of the extraction process. Based on the results, it can be concluded that this technique is suitable for obtaining bioactive substances.

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Section: Introductionmentioning

confidence: 99%

"Kinetic Modelling of Ultrasound-Assisted Extraction of Bioactive Compounds from Helichrysum Arenarium"

Bajrami¹

2023

BJSTR

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“…Figure 1. Schematic representation of the design of experiments applied during ultrasound-assisted extraction of bioactive compounds from plant-based materials (Adapted from[68,83,149]). …”

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confidence: 99%

Design of Experiments for Optimizing Ultrasound-Assisted Extraction of Bioactive Compounds from Plant-Based Sources

Anaya-Esparza,

Aurora-Vigo,

Villagrán

et al. 2023

Molecules

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Plant-based materials are an important source of bioactive compounds (BC) with interesting industrial applications. Therefore, adequate experimental strategies for maximizing their recovery yield are required. Among all procedures for extracting BC (maceration, Soxhlet, hydro-distillation, pulsed-electric field, enzyme, microwave, high hydrostatic pressure, and supercritical fluids), the ultrasound-assisted extraction (UAE) highlighted as an advanced, cost-efficient, eco-friendly, and sustainable alternative for recovering BC (polyphenols, flavonoids, anthocyanins, and carotenoids) from plant sources with higher yields. However, the UAE efficiency is influenced by several factors, including operational variables and extraction process (frequency, amplitude, ultrasonic power, pulse cycle, type of solvent, extraction time, solvent-to-solid ratio, pH, particle size, and temperature) that exert an impact on the molecular structures of targeted molecules, leading to variations in their biological properties. In this context, a diverse design of experiments (DOEs), including full or fractional factorial, Plackett–Burman, Box-Behnken, Central composite, Taguchi, Mixture, D-optimal, and Doehlert have been investigated alone and in combination to optimize the UAE of BC from plant-based materials, using the response surface methodology and mathematical models in a simple or multi-factorial/multi-response approach. The present review summarizes the advantages and limitations of the most common DOEs investigated to optimize the UAE of bioactive compounds from plant-based materials.

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State-of-the-art review on recent advances in polymer engineering: modeling and optimization through response surface methodology approach

et al. 2022

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Modeling approaches to optimize the recovery of polyphenols using ultrasound-assisted extraction

Cited by 5 publications

References 48 publications

"Kinetic Modelling of Ultrasound-Assisted Extraction of Bioactive Compounds from Helichrysum Arenarium"

"Kinetic Modelling of Ultrasound-Assisted Extraction of Bioactive Compounds from Helichrysum Arenarium"

Design of Experiments for Optimizing Ultrasound-Assisted Extraction of Bioactive Compounds from Plant-Based Sources

State-of-the-art review on recent advances in polymer engineering: modeling and optimization through response surface methodology approach

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