Modeling of hemodynamic changes in the aneurysm of the middle cerebral artery depending on the pathology of the parent artery

Abstract

Model 1 showed that the flow redistribution did not significantly impact on the risk of rupture after the parent artery was turned off and blood pressure was increased in both aneurysms by 3 mm Hg. Model 2, in which the aneurysms were combined with a direct arteriovenous drainage with low peripheral resistance, showed that turning off the parent artery and pathological drainage led to the serious reduction in the venous drainage flow and it's increasing in the parent artery by about 60% that significantly increased the risk of rupture.

Noninvasive Assessment of Fractional Flow Reserve According to Coronary Computed Tomography Angiography Using Hydrodynamic Calculations

“…Расчетная модель кровотока основывалась на практике гемодинамических расчетов в церебральных артериях [7]. В вычислительной схеме упругость стенок сосудов не учитывалась, кровь рассматривалась как однородная несжимаемая ньютоновская жидкость с постоянной плотностью -1080 кг/м3 и вязкостью -0,00388 Па•с [8].…”