Modelling the decreasing coronary heart disease mortality in Sweden between 1986 and 2002

Abstract

More than half of the substantial CHD mortality decrease in Sweden between 1986 and 2002 was attributable to reductions in major risk factors, mainly a large decrease in total serum cholesterol. These findings emphasize the value of a comprehensive strategy that promotes primary prevention and evidence-based medical treatments, especially secondary prevention.

Declining cardiovascular mortality and increasing obesity: a paradox

“…3 Accordingly, although obese people still have more risk factors (except for smoking) than lean people, the level of serum cholesterol is much lower than in previous decades. The main reason, thus, for the continuing decline in mortality associated with coronary artery disease seems to be driven by changes in diet, presumably the consumption of less saturated fat, and by less smoking.…”

“…Modelling studies suggest that we can attribute 44% to 58% of the decline to population changes in risk factors, mainly cholesterol levels and smoking, and 36% to 47% to treatments. [1][2][3] However, simultaneously, and seemingly at odds with these developments, is the increasing prevalence of obesity, 4,5 which is a major risk factor for cardiovascular disease.…”

Misvisende om kosthold i ny nasjonal retningslinje for forebygging av hjerte- og karsykdommer

“…Én studie av 52 land viste at ni modifiserbare risikofaktorer forklarte 90 prosent av den globale variasjonen i hjerteinfarkt 23 . Mye av de siste 40 års nedgang i hjerte-og karsykdom og dødelighet av hjerte-og karsykdom har i mange land blitt forklart med forbedringer i de nevnte risikofaktorene, spesielt lavere gjennomsnittlige kolesterol nivåer [35][36][37][38][39] . I Tromsø-undersøkelsen kunne 2/3 av den lavere insidensen av hjerteinfarkt og plutselig hjertedød mellom 1995 og 2010 tilskrives bedring av risikofaktorer i befolkningen 36 .…”

Key Provisions of the New (2016) European Guidelines for Management of Dyslipidemias and Comments

“…Снижение смертности от ССЗ (более чем наполовину) в последние 30 лет объясняют уменьшением уровней ХС и снижением средних значений АД, а также уменьшением числа курящих [3][4][5]. Однако этой положительной тен-денции частично противостоит наблюдаемое в последнее десятилетие увеличение других ФР -ожирения и сахар-ного диабета (СД) 2-го типа.…”