Water shortage and pollution have become prominent in the arid regions of northwest China, seriously affecting human survival and sustainable development. The Bosten Lake basin has been considered as an example of an arid region in northwest China, and the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) model has been used to quantitatively evaluate the future water yield and water purification services for four representative concentration pathways (RCP) scenarios. The results show that for the four RCP scenarios, the annual average precipitation in 2020–2050 decreases compared to that in 1985–2015; the area of cultivated land and unused land decreases, and the area of other land-use types increases from 2015 to 2050. The water yield service reduces, while the water purification service increases from 2015 to 2050 in the Bosten Lake basin. In 2050, the water yield and water purification services are the best for the RCP6.0 scenario, and are the worse for the RCP4.5 scenario and RCP8.5 scenario, respectively. The distribution of the water yield and water purification services show a gradual decline from northwest to southeast.