Modern microfluidic approaches for determination of ions

Shi, Huanhuan; Jiang, Shaofeng; Liu, Bo; Liu, Zhengchun; Reis, Nuno M.

doi:10.1016/j.microc.2021.106845

Cited by 14 publications

(4 citation statements)

References 155 publications

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“…In addition, since tears include many biomarkers, contact lens sensors can be used to directly measure different parameters such as glucose, urea, protein concentrations, ions [ 112 ], IOP, and corneal temperature, noninvasively. Microelectromechanical machining technology [ 113 ] enables contact lenses with detection electrodes and tiny structures to be used as wearable devices for biomarkers monitoring and delivery of drugs for treating eye diseases [ 114 ].…”

Section: In Vitro Biomechanical Study Methods Of Eye Tissuementioning

confidence: 99%

Biomechanical analysis of ocular diseases and its in vitro study methods

Zhao

Yan

et al. 2022

BioMed Eng OnLine

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Ocular diseases are closely related to the physiological changes in the eye sphere and its contents. Using biomechanical methods to explore the relationship between the structure and function of ocular tissue is beneficial to reveal the pathological processes. Studying the pathogenesis of various ocular diseases will be helpful for the diagnosis and treatment of ocular diseases. We provide a critical review of recent biomechanical analysis of ocular diseases including glaucoma, high myopia, and diabetes. And try to summarize the research about the biomechanical changes in ocular tissues (e.g., optic nerve head, sclera, cornea, etc.) associated with those diseases. The methods of ocular biomechanics research in vitro in recent years are also reviewed, including the measurement of biomechanics by ophthalmic equipment, finite element modeling, and biomechanical analysis methods. And the preparation and application of microfluidic eye chips that emerged in recent years were summarized. It provides new inspiration and opportunity for the pathogenesis of eye diseases and personalized and precise treatment.

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Section: In Vitro Biomechanical Study Methods Of Eye Tissuementioning

confidence: 99%

Biomechanical analysis of ocular diseases and its in vitro study methods

Zhao

Yan

et al. 2022

BioMed Eng OnLine

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“…In addition, recent investigations have also emphasized flow-based chemiluminescence (CL) assays involving microfluidic devices. 33,[50][51][52] When a molecule undergoes exothermic excitation to reach the singlet excited state, it emits CL characterized by electromagnetic radiation with a distinct wavelength, mainly falling within the visible and near-infrared range. The emitted light's intensity can be correlated with the concentration of the analyte.…”

Section: Detection Techniquesmentioning

confidence: 99%

Microfluidics in environmental analysis: advancements, challenges, and future prospects for rapid and efficient monitoring

Aryal,

Hefner,

Martinez

et al. 2024

Lab Chip

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“…The work in [ 171 ] showed that the flexible laminated graphene paper electrode was an economical and efficient alternative to glassy carbon and platinum-wire electrodes and showed that the performance of the flexible laminated graphene paper, K + selective solid-contact ISE, was comparable to the most advanced solid-contact ISE. Microfluidics, characterized by fluid manipulation in submillimeter channels/reactors, are of great concern in many areas such as polymer synthesis, fine chemical processing, and biomedicine [ 172 , 173 , 174 ]. The study in [ 175 ] introduced a new concept of solid reference electrodes integrated with microfluidic paper-based sampling and was successfully used for ion determination in environmental and clinically relevant samples.…”

Section: Prospection Of Crop Detection Applicationsmentioning

confidence: 99%

Unlocking All-Solid Ion Selective Electrodes: Prospects in Crop Detection

Zhai

Luo

et al. 2022

Sensors

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This paper reviews the development of all-solid-state ion-selective electrodes (ASSISEs) for agricultural crop detection. Both nutrient ions and heavy metal ions inside and outside the plant have a significant influence on crop growth. This review begins with the detection principle of ASSISEs. The second section introduces the key characteristics of ASSISE and demonstrates its feasibility in crop detection based on previous research. The third section considers the development of ASSISEs in the detection of corps internally and externally (e.g., crop nutrition, heavy metal pollution, soil salinization, N enrichment, and sensor miniaturization, etc.) and discusses the interference of the test environment. The suggestions and conclusions discussed in this paper may provide the foundation for additional research into ion detection for crops.

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Modern microfluidic approaches for determination of ions

Cited by 14 publications

References 155 publications

Biomechanical analysis of ocular diseases and its in vitro study methods

Biomechanical analysis of ocular diseases and its in vitro study methods

Microfluidics in environmental analysis: advancements, challenges, and future prospects for rapid and efficient monitoring

Unlocking All-Solid Ion Selective Electrodes: Prospects in Crop Detection

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