Modification and Characterization of Amprotab With Hydroxypropyl Methylcellulose Using Citric Acid as Crosslinking Agent

Abstract

Objective: This study aimed to characterize Amprotab that has been modified chemically, physically, and mechanically using HPMC and citric acid. Methods: The study is divided into two parts: three control formulas and three treatment formulas. Control Formula 1 (without HPMC and citric acid), Control 2 (HPMC 1.5 g without citric acids), Control 3 (citric acid 1.5 g without HPMC), Formula 1 (HPMC 4.5 g and citric acid 4.5 g). By analyzing Fourier Transform Infrared (FTIR), scanning electron microscopy (SEM), swelling, tensile strength, stability (freeze-thaw cycles), X-ray Diffraction (XRD), and Thermogravimetric Analysis (TGA), copolymers modified by Amprotab were characterized. Results: An FTIR analysis revealed that crosslinking of Amprotab was formed in formulas 1, 2, and 3 with prominent C=O ester bonds at peaks of 1730.22 cm-1, 1733.12 cm-1, and 1736.01 cm-1. The surface morphology of the modified cassava amylum CROSSLINKED COPOLYMER (CCA) was coarser. CCA's expanding power is less than that of natural Amprotab, whereas CCA's tensile strength is greater. Conclusion: CCA has a high value for syneresis. XRD analysis revealed that CCA has a crystal diffraction pattern of type B, and TGA analysis revealed that CCA is stable at high temperatures.