Modification of Polyacrylonitrile Particles and Grafted Films with Oxazolines

Cabrera, Andrés; Böhme, Liz M.; Schmidt‐Naake, Gudrun

doi:10.1002/macp.200400340

Cited by 4 publications

(2 citation statements)

References 25 publications

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“…A substituted 2-aminoalcohol, namely 2-amino-2-ethyl-1,3-propanediol, was reacted with the nitrile groups of poly(acrylonitrile)s by Schmidt-Naake et al, yielding 2-oxazoline moieties attached to the polyolefin backbone [90]. The modified poly(acrylonitrile) particle surfaces were subsequently reacted with methyl triflate in order to graft pEtOx on those surfaces.…”

Section: Grafting From Pending 2-oxazoline Unitsmentioning

confidence: 99%

Design Strategies for Functionalized Poly(2-oxazoline)s and Derived Materials

2013

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Abstract:The polymer class of poly(2-oxazoline)s currently is under intensive investigation due to the versatile properties that can be tailor-made by the variation and manipulation of the functional groups they bear. In particular their utilization in the biomedic(in)al field is the subject of numerous studies. Given the mechanism of the cationic ring-opening polymerization, a plethora of synthetic strategies exists for the preparation of poly(2-oxazoline)s with dedicated functionality patterns, comprising among others the functionalization by telechelic end-groups, the incorporation of substituted monomers into (co)poly(2-oxazoline)s, and polymeranalogous reactions. This review summarizes the current state-of-the-art of poly(2-oxazoline) preparation and showcases prominent examples of poly(2-oxazoline)-based materials, which are retraced to the desktop-planned synthetic strategy and the variability of their properties for dedicated applications.

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Section: Grafting From Pending 2-oxazoline Unitsmentioning

confidence: 99%

Design Strategies for Functionalized Poly(2-oxazoline)s and Derived Materials

2013

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“…Different Oxazoline modified copolymers are reported as reactive compatibilizer in blends of oxa ABS/PC, Oxa SAN/PC, Oxa SAN and ABS/PA, OxaSAN/(PE‐co‐MA) and Oxa NBR/partially hydrolyzed EVA (EVALVA) . G. S. Naake reported the synthesis of oxazoline modified PAN and its copolymers as macroinitiators for the cationic ring opening grafting of oxazolines to obtain poly (N‐acylethylenimine) side chains. These products are found to be interesting substrates for immobilization of biological substances.…”

Section: Nitrile Group Modifications In Polymersmentioning

confidence: 99%

An overview of synthetic modification of nitrile group in polymers and applications

Sruthi

Anas

2020

Journal of Polymer Science

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The physicochemical properties of polymers are mainly dependent on the nature of polymer backbone and/or pendant groups linked to the main chain. Therefore, synthetic modification of these functional groups via post functionalization is an important approach for obtaining novel polymeric systems with improved properties and targeted applications. In this context, the synthetic modifications of nitrile group in polymers into various useful functionalities have received considerable attention and several interesting applications of the resulting polymers have been identified. The majority of the studies are based on Polyacrylonitrile (PAN), and some isolated examples of nitrile functionalization in copolymers such as Poly (Styrene-co-Acrylonitrile) (SAN), Poly (Acrylonitrile-co-Butadiene-co-Styrene (ABS) and Nitrile Rubber (NBR) are available. These synthetic modifications are mainly accomplished by the reactions such as Nucleophilic addition, cycloaddition, reduction, and hydrolysis using various reagents. These studies describing the post-polymerization modifications of nitrile group in polymers reported during the last three decades are covered in this review.

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Gelatin hydrogels: enhanced biocompatibility, drug release and cell viability

Rathna

2007

J Mater Sci: Mater Med

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Biodegradability and enhanced biocompatibility with pH-sensitivity of hydrogels are becoming very important issues for biomaterials applications so as to minimize the host-body reactions such as, inflammatory, antigenic, and immunogenic problems. This study involves development of hydrogel matrices of gelatin conjugated/modified with highly hydrophilic, pH-sensitive and biocompatible polymer, poly (2-ethyl-2-oxazoline) and glyoxylic acid respectively. Various compositions of gelatin conjugated/modified with poly (2-ethyl-2-oxazoline) (gp) and glyoxylic acid (gg) were synthesized. The swelling kinetics, cell viability and drug release capability from the gels at pH 4.5 and 7.4 were investigated. The results of swelling kinetics showed that, both the degree of swelling (DS) and the maximum degree of swelling (MDS) increased as function of modification (increase in modification) and pH with an increase of time, which is due to increase in ionic groups. The drug-release (1% chlorhexidine) studies at pH 7.4 and 4.5 confirmed a proportional drug release with an increase in degree of swelling. The results of in-vitro cytotoxicity tests using mouse embryonic 3T3 fibroblast cells indicated, an improved cell viability for gelatin gels conjugated/modified with poly (2-ethyl-2-oxazoline) (gp) and glyoxylic acid (gg) gels, when compared with 1% glutaraldehyde cross-linked gelatin gels (gx). Hence, cross-linked gelatin gels can be replaced with gp/gg for potential use in biomedical applications as a matrix for drug delivery.

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Modification of Polyacrylonitrile Particles and Grafted Films with Oxazolines

Cited by 4 publications

References 25 publications

Design Strategies for Functionalized Poly(2-oxazoline)s and Derived Materials

Design Strategies for Functionalized Poly(2-oxazoline)s and Derived Materials

An overview of synthetic modification of nitrile group in polymers and applications

Gelatin hydrogels: enhanced biocompatibility, drug release and cell viability

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