Modified Rapid Deployment Hemostat Terminates Bleeding From Hepatic Rupture in Third Trimester

King, David R.; Moya, Mark M. De; McKenney, Mark; Cohn, Stephen M.

doi:10.1097/01.ta.0000195491.92467.dd

Cited by 9 publications

(2 citation statements)

References 23 publications

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“…22,23 Liver transplantation is necessary when liver biopsies reveal worsening diffuse hepatic necrosis with no identifiable normal parenchyma remaining; the clinical/laboratory findings of the patients include deterioration and fulminant hepatic failure and when hemorrhage cannot be arrested during laparotomy. 23,24 More recently, in cases where bleeding is confined to 1 lobe of the liver, radiographically directed arterial embolization has been successful. 25 It might be preferred in critically ill patients with severe coagulopathy.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and Surgical Management of Spontaneous Hepatic Rupture Associated with HELLP Syndrome

Pavlis¹,

Aloizos²,

Aravosita³

et al. 2009

Journal of Surgical Education

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Section: Discussionmentioning

confidence: 99%

Diagnosis and Surgical Management of Spontaneous Hepatic Rupture Associated with HELLP Syndrome

Pavlis¹,

Aloizos²,

Aravosita³

et al. 2009

Journal of Surgical Education

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“…The modified RDH bandage, which contains higher concentrations of the active product than the RDH bandage, brought about haemostasis within 5 min in all but one of these patients. It has also been successfully used in the treatment of a spontaneous liver injury arising from pre‐eclampsia in the third trimester of pregnancy, where it was compared with, and found to be superior to, Surgicel ® Nu‐Knit101.…”

Section: Polysaccharide‐based Haemostatsmentioning

confidence: 99%

Topical haemostatic agents

Seyednejad

Imani

Jamieson

et al. 2008

British Journal of Surgery

189

167

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Background: A variety of local haemostatic agents is now available to stop troublesome bleeding. These agents are indicated for use during surgical interventions where conventional methods of haemostasis are not applicable because of the site of surgery or the degree of bleeding.Method: A literature search using the PubMed and ISI Web of Knowledge databases identified relevant studies on topical haemostatic agents. Manufacturers' recommendations were also sought through commercial websites.Results and conclusion: A significant body of evidence now exists to support the use of topical haemostatic agents in a wide variety of clinical situations. The advantages and disadvantages of many of these agents are highlighted.

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Hemostatic effects of Microporous Polysaccharide Hemosphere® in a rat model with severe femoral artery bleeding

et al. 2007

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An appropriate hemostatic dressing for prehospital use should lower mortality due to uncontrolled hemorrhage. In this study, the investigators explored the hemostatic effects of Microporous Polysaccharide Hemosphere (MPH) applied in a rat model with severe femoral artery bleeding. Twelve rats were randomly assigned to MPH and control groups: The femoral artery of each rat was pierced to initiate bleeding. Then, 0.25 g MPH was poured into the bleeding site. A 200-g scale weight was placed over the bleeding site for 30 sec. At 30-sec intervals, the scale weight was removed, and hemostasis was assessed visually. After 30 sec, if the bleeding had ceased, the test was scored and checked as "passed at 30 sec." If the bleeding had not stopped, the same procedures were repeated a maximum of 3 times. If hemostasis could not be achieved even after the third application, the test was scored as failed. The same sequence of procedures was repeated for the control group without use of MPH and with only standard compression. Application of MPH resulted in complete control of bleeding in 2 of 6, 4 of 6, and 6 of 6 rats at 30, 60, and 90 sec, respectively. In the control group, however, hemostasis could not be achieved in all 6 rats, even at 90 sec. The difference between the 2 groups was statistically significant (P=.007). Application of MPH and compression with a scale weight significantly decreased the time of hemostasis in the rat model with femoral arterial bleeding.

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Modified Rapid Deployment Hemostat Terminates Bleeding From Hepatic Rupture in Third Trimester

Cited by 9 publications

References 23 publications

Diagnosis and Surgical Management of Spontaneous Hepatic Rupture Associated with HELLP Syndrome

Diagnosis and Surgical Management of Spontaneous Hepatic Rupture Associated with HELLP Syndrome

Topical haemostatic agents

Hemostatic effects of Microporous Polysaccharide Hemosphere® in a rat model with severe femoral artery bleeding

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