Modified slide tracheoplasty for the management of tracheobroncopathia osteochondroplastica

Kutlu, Cemal Asım; Yeginsu, Ali; Özalp, Tevrat; Baran, Reha

doi:10.1016/s1010-7940(01)01080-6

Cited by 21 publications

(9 citation statements)

References 4 publications

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“…Except one patient died of lung cancer and symptoms of one with hoarseness unchanged, the rest 12 patients remitted to some extent. Bronchoscopic correction and surgical approaches should be resorted to in the case of severe constriction in the lumen of central airways [15], [32], [46], [47].…”

Section: Discussionmentioning

confidence: 99%

A Clinical Study of Tracheobronchopathia Osteochondroplastica: Findings from a Large Chinese Cohort

Zhu

Huang

et al. 2014

PLoS ONE

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Background and Study AimsTracheobronchopathia osteochondroplastica (TO) is an uncommon disease of the tracheobronchial system that leads to narrowing of the airway lumen from cartilaginous and/or osseous submucosal nodules. The aim of this study is to perform a detailed review of this rare disease in a large cohort of patients with TO proven by fiberoptic bronchoscopy from China.Patients and MethodsRetrospective chart review was performed on 41,600 patients who underwent bronchoscopy in the Department of Respiratory Medicine of Changhai Hospital between January 2005 and December 2012. Cases of TO were identified based on characteristic features during bronchoscopic examination.Results22 cases of bronchoscopic TO were identified. Among whom one-half were male and the mean age was 47.45±10.91 years old. The most frequent symptoms at presentation were chronic cough (n = 14) and increased sputum production (n = 10). Radiographic abnormalities were observed in 3/18 patients and findings on computed tomography consistent with TO such as beaded intraluminal calcifications and/or increased luminal thickenings were observed in 18/22 patients. Patients were classified into the following categories based on the severity of bronchoscopic findings: Stage I (n = 2), Stage II (n = 6) and Stage III (n = 14). The result that bronchoscopic improvement was observed in 2 patients administered with inhaled corticosteroids suggested that resolution of this disease is possible.ConclusionsTO is a benign disease with slow progression, which could be roughly divided into 3 stages on the basis of the characteristic endoscopic features and histopathologic findings. Chronic inflammation was thought to be more important than the other existing plausible hypotheses in the course of TO. Inhaled corticosteroids might have some impact on patients at Stage I/II.

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Section: Discussionmentioning

confidence: 99%

A Clinical Study of Tracheobronchopathia Osteochondroplastica: Findings from a Large Chinese Cohort

Zhu

Huang

et al. 2014

PLoS ONE

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“…Özellikle yan grafide trakeobronşiyal ağaç-ta kalsifikasyon görülebilir (9). BT' de havayollarının ön ve yan duvarlarında düzensiz kalsifikasyonlar içeren nodüller "beaded appereance", hava yolu kenar düzeni bozukluğu izlenir (10,11). Her iki olguda da toraks BT' de trakea duvarında düzensizlik ve kalsifikasyon dikkati çekti.…”

Section: şEkil 6: Toraks Bt Mediasten Kesitinde Ana Karina Hizasındaunclassified

Tracheobronchopatia Ostecondroplastica: two cases studies

Baha¹,

Körlü²,

Köktürk³

et al. 2014

Respir Case Rep

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Trakeobronkopatia Osteokondroplastika (TO) trakea ve bronş submukozasında kemik ve kıkırdak nodülle-rin varlığı ile karakterize, nadir görülen, benign bir durumdur. Hastalık daha çok 50 yaş üzeri erkeklerde görülür ve çoğu zaman asemptomatiktir. Bazı olgularda sık tekrarlayan enfeksiyonlar görülebilirken bazı olgularda bronşial aşırı duyarlılık veya hemoptizi izlenebilir. Bu olgu sunumunda TO teşhisi koyulan iki hastanın fiberoptik bronkoskopik (FOB), klinik ve radyolojik özellikleri tartışılmıştır. Yirmi yaşında kadın olgu, 2,5 yıldır olan kuru öksürük şikayeti ile başvur-du. Solunum fonksiyon testi normaldi. Toraks bilgisayarlı tomografisinde (BT), trakea ve ana bronşlarda trakea posterior membranının korunduğu yaygın kalsifikasyonlar görüldü. FOB'da tüm trakeal hat boyunca multipl, beyaz renkli polipoid yapılar izlendi. Olgu inhaler steroid tedavisi altında semptomsuz olarak izlenmektedir. Hemoptizi şikayeti ile başvuran 52 yaşında kadın hastanın Toraks BT'sinde trakea lümeninde yaygın nodüler görünüm izlendi. FOB'da endobronşiyal lezyon izlenmedi ancak tüm trakeal hatta mukozadan kabarık, beyaz renkli lezyonlar görüldü. Hasta hemoptizi tekrarı olmadan izlenmektedir. Tracheobronchopathia Osteochondroplastica (TO) is a rare, benign condition characterized by the presence of bony and cartilaginous nodules in the tracheal and bronchial submucosa. Tracheobroncopatia Osteocondroblastica is usually asymptomatic and particularly affects men above 50 years of age. Patients may present with recurrent infections, symptoms of bronchial hyperresponsiveness and with hemoptysis. Here, two patients with tracheobronchopatia ostecondroplastica are discussed regarding fiberoptic bronchoscopic, radiologic and clinical features of the disease. A-20-year-old female patient presented to our clinic with symptom of dry cough which had been present for 2,5 years. Pulmonary function test were found to be normal. Thorax CT revealed diffuse calcifications in trachea and main bronchi with preserved posterior membrane. Multiple, polypoid and whitecolored lesions were detected in all tracheal area with fiberoptic bronchoscopy. Patient is being followed asymptomatic under inhaler steroid therapy. A-52-year-old female patient admitted to our clinic with symptom of hemoptysis. Thorax CT revealed diffuse tracheal nodules. Polypoid white-colored lesions were detected in tracheal submucosa with fiberoptic bronchoscopy. The patient is being followed without recurrence of hemoptysis.

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“…En pacientes con obstrucción severa de la vía aérea se han realizado terapias broncoscópicas 1,2,4,8,10,11 e incluso se ha intentado la resolución quirúrgica 1,2,12,13 . No se dispone de guías clínicas estandarizadas para el manejo de esta enfermedad [1][2][3] .…”

Section: Tratamiento De Tbocunclassified

“…En pacientes con severa obstrucción de la vía aérea se han realizado terapias broncoscópicas como ablación con láser, crioterapia o divulsión mecánica de las lesiones 1,2,4,8,10,11 . También se ha intentado la resolución quirúrgica 1,2,12,13 , siendo no efectiva en muchas ocasiones, debido al compromiso difuso y multisegmentario de la vía aérea. Existen reportes escasos de manejo mediante radioterapia 1,2 .…”

Section: Introductionunclassified

Traqueobroncopatía osteocondroplástica: Reporte de un caso y revisión de la literatura

2010

Rev. Otorrinolaringol. Cir. Cabeza Cuello

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RESUMENLa traqueobroncopatía osteocondroplástica es una enfermedad benigna poco frecuente, de etiología incierta, caracterizada por múltiples nódulos submucosos cartilaginosos u óseos en tráquea, bronquios principales y menos frecuentemente, región subglótica y laringe. La presentación clínica de la enfermedad varía desde pacientes asintomáticos, hasta enfermedad severa con obstrucción de la vía aérea. El gold standard para el diagnóstico es la broncoscopía, donde característicamente se visualiza la presencia de múltiples nódulos submucosos que se proyectan hacia el lumen de la vía aérea. La biopsia no es requisito para el diagnóstico. El tratamiento de la enfermedad está dirigido habitualmente al manejo sintomático. En pacientes con severa obstrucción de la vía aérea se han realizado terapias broncoscópicas como ablación con láser, crioterapia o divulsión mecánica de las lesiones. También se ha intentado la resolución quirúrgica, siendo generalmente inefectiva. Presentamos el caso clínico de un paciente evaluado en nuestro servicio, en quien se realizó diagnóstico de traqueobroncopatía osteocondroplástica con compromiso tráqueo-bronquial y subglótico.Palabras clave: Traqueobroncopatía osteocondroplástica, estenosis subglótica ABSTRACTTracheobronchopathy osteochondroplastica is a rare benign disease of uncertain etiology, characterized by multiple cartilaginous or bony submucosal nodules in trachea, bronchi and, less frequently, subglottic region and larynx. The clinical presentation of the disease varies from asymptomatic patients to severe disease with airway obstruction. The gold standard for diagnosis is bronchoscopy, which typically displays the presence of multiple submucosal nodules that project into the lumen of the airway. Biopsy is not required for diagnosis. The treatment of the disease is usually symptomatic management. In patients with severe airway obstruction bronchoscopic therapies such as laser ablation, cryotherapy or mechanical removal have been performed. Surgical resolution has also been attempted, being generally ineffective. We

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Modified slide tracheoplasty for the management of tracheobroncopathia osteochondroplastica

Cited by 21 publications

References 4 publications

A Clinical Study of Tracheobronchopathia Osteochondroplastica: Findings from a Large Chinese Cohort

A Clinical Study of Tracheobronchopathia Osteochondroplastica: Findings from a Large Chinese Cohort

Tracheobronchopatia Ostecondroplastica: two cases studies

Traqueobroncopatía osteocondroplástica: Reporte de un caso y revisión de la literatura

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