“…This stereochemistry at C16 had been determined by Allison et al (1967) correctly through the ORD measurements (see above). Ring E is connected to ring D through the position at C16.…”
Section: Commentmentioning
confidence: 90%
“…Compound (I) was prepared by the Robinson annelation procedure from 16-hydroxymethylidene-3-methoxyestra-1,3,5(10)-trien-17-one by a known procedure (Allison et al, 1967). The crystal used for X-ray structure analysis was obtained by recrystallization of (I) from chloroform±ether±hexane (1:1:1).…”
Section: Methodsmentioning
confidence: 99%
“…The title compound, (I), was synthesized by Allison et al (1967) as a potential anti-in¯ammatory agent. At the time, the stereochemistry of the introduced chirality at C16 was determined through ORD spectroscopic analysis of the n±%* transition of the C17(20)-en-21-one system.…”
Key indicatorsSingle-crystal X-ray study T = 123 K Mean '(C±C) = 0.004 A Ê R factor = 0.034 wR factor = 0.073 Data-to-parameter ratio = 9.0 For details of how these key indicators were automatically derived from the article, see
“…This stereochemistry at C16 had been determined by Allison et al (1967) correctly through the ORD measurements (see above). Ring E is connected to ring D through the position at C16.…”
Section: Commentmentioning
confidence: 90%
“…Compound (I) was prepared by the Robinson annelation procedure from 16-hydroxymethylidene-3-methoxyestra-1,3,5(10)-trien-17-one by a known procedure (Allison et al, 1967). The crystal used for X-ray structure analysis was obtained by recrystallization of (I) from chloroform±ether±hexane (1:1:1).…”
Section: Methodsmentioning
confidence: 99%
“…The title compound, (I), was synthesized by Allison et al (1967) as a potential anti-in¯ammatory agent. At the time, the stereochemistry of the introduced chirality at C16 was determined through ORD spectroscopic analysis of the n±%* transition of the C17(20)-en-21-one system.…”
Key indicatorsSingle-crystal X-ray study T = 123 K Mean '(C±C) = 0.004 A Ê R factor = 0.034 wR factor = 0.073 Data-to-parameter ratio = 9.0 For details of how these key indicators were automatically derived from the article, see
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.