Modular Microfluidic Paper‐Based Devices for Multi‐Modal Cascade Catalysis

Andersen, Nalin I.; Artyushkova, Kateryna; Matanović, Ivana; Chavez, Madelaine Seow; Hickey, David P.; Abdelloui, Sofiene; Minteer, Shelley D.; Atanassov, Plamen

doi:10.1002/celc.201900211

Cited by 8 publications

(4 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Surface-enhanced Raman spectroscopy (SERS) is a technology that enhances the surface sensitivity of Raman scattering using molecules adsorbed on rough metal surfaces or nanostructures, such as plasma magnetic silica nanotubes [ 73 ]. This technology has a high sensitivity [ 74 , 75 ] and enables detection at a single-molecule level [ 76 ]. However, due to the complex composition of clinical samples, the enhanced surface often does not function as expected on paper materials.…”

Section: μPads Based On Different Detection Methodsmentioning

confidence: 99%

Research Progress and Future Trends of Microfluidic Paper-Based Analytical Devices in In-Vitro Diagnosis

et al. 2022

View full text Add to dashboard Cite

In vitro diagnosis (IVD) has become a hot topic in laboratory research and achievement transformation. However, due to the high cost, and time-consuming and complex operation of traditional technologies, some new technologies are being introduced into IVD, to solve the existing problems. As a result, IVD has begun to develop toward point-of-care testing (POCT), a subdivision field of IVD. The pandemic has made governments and health institutions realize the urgency of accelerating the development of POCT. Microfluidic paper-based analytical devices (μPADs), a low-cost, high-efficiency, and easy-to-operate detection platform, have played a significant role in advancing the development of IVD. μPADs are composed of paper as the core material, certain unique substances as reagents for processing the paper, and sensing devices, as auxiliary equipment. The published reviews on the same topic lack a comprehensive and systematic introduction to μPAD classification and research progress in IVD segmentation. In this paper, we first briefly introduce the origin of μPADs and their role in promoting IVD, in the introduction section. Then, processing and detection methods for μPADs are summarized, and the innovative achievements of μPADs in IVD are reviewed. Finally, we discuss and prospect the upgrade and improvement directions of μPADs, in terms of portability, sensitivity, and automation, to help researchers clarify the progress and overcome the difficulties in subsequent μPAD research.

show abstract

Section: μPads Based On Different Detection Methodsmentioning

confidence: 99%

Research Progress and Future Trends of Microfluidic Paper-Based Analytical Devices in In-Vitro Diagnosis

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Comparted to glass or PDMS microchip, paper-based microfluidics are inexpensive, easy to use, and suit for on-site/point-of need application [62]. To integrate SERS-active materials with paper microfluidics, different deposition [63,64] and printing techniques [33,34,65,66] are applied. For instance, through physical vapor deposition, Torul et al [64] embedded Au nanorod on paper-based microchannels for glucose SERS detection.…”

Section: Build-in Detection Microchipsmentioning

confidence: 99%

“…The AgNPs embed in their build-in SERS detection zones act as both catalyst and SERS reporter. To address multistep reaction monitoring, Andersen et al [65] created a paperbased microreactor having three SERS detection zones for monitoring the oxidation processes of glycerol to carbon dioxide. The combination of microfluidic reactor and SERS detection turns out to be potential and usable approach for monitoring chemical reaction in a confined space, for example, micro-/nanochannel.…”

Section: 42mentioning

confidence: 99%

Recent progress of microfluidics in surface‐enhanced Raman spectroscopic analysis

Xia

2021

J of Separation Science

View full text Add to dashboard Cite

Surface-enhanced Raman spectroscopy is a significant analytical tool capable of fingerprint identification of molecule in a rapid and ultrasensitive manner. However, it is still hard to meet the requirements of practical sample analysis.The introduction of microfluidics can effectively enhance the performance of surface-enhanced Raman spectroscopy in complex sample analysis including reproducibility, selectivity, sensitivity, and speed. This review summarizes the recent progress of microfluidics in surface-enhanced Raman spectroscopic analysis through four combination approaches. First, microfluidic synthetic techniques offer uniform nano-/microparticle fabrication approaches for reproductive surface-enhanced Raman spectroscopic analysis. Second, the integration of microchip and surface-enhanced Raman spectroscopic substrate provides advanced devices for sensitive and efficient detection. Third, microfluidic sample preparations enable rapid separation and preconcentration of analyte prior to surface-enhanced Raman spectroscopic detection. Fourth, highly integrated microfluidic devices can be employed to realize multistep surface-enhanced Raman spectroscopic analysis containing material fabrication, sample preparation, and detection processes. Furthermore, the challenges and outlooks of the application of microfluidics in surface-enhanced Raman spectroscopic analysis are discussed.

show abstract

“…In terms of the breadth of modular microfluidic systems, innovative forms of modular microfluidic systems can be further studied, such as paper-based modular microfluidics [109,110], digital modular microfluidics [111], template modularity-based microfluidics [112], and improved inter-module connections using advanced materials such as self-healing hydrogels [113,114] and superhydrophobic materials [115];…”

mentioning

confidence: 99%

Modular Microfluidics: Current Status and Future Prospects

Lai

Yang

et al. 2022

Micromachines

View full text Add to dashboard Cite

This review mainly studies the development status, limitations, and future directions of modular microfluidic systems. Microfluidic technology is an important tool platform for scientific research and plays an important role in various fields. With the continuous development of microfluidic applications, conventional monolithic microfluidic chips show more and more limitations. A modular microfluidic system is a system composed of interconnected, independent modular microfluidic chips, which are easy to use, highly customizable, and on-site deployable. In this paper, the current forms of modular microfluidic systems are classified and studied. The popular fabrication techniques for modular blocks, the major application scenarios of modular microfluidics, and the limitations of modular techniques are also discussed. Lastly, this review provides prospects for the future direction of modular microfluidic technologies.

show abstract

Modular Microfluidic Paper‐Based Devices for Multi‐Modal Cascade Catalysis

Cited by 8 publications

References 34 publications

Research Progress and Future Trends of Microfluidic Paper-Based Analytical Devices in In-Vitro Diagnosis

Research Progress and Future Trends of Microfluidic Paper-Based Analytical Devices in In-Vitro Diagnosis

Recent progress of microfluidics in surface‐enhanced Raman spectroscopic analysis

Modular Microfluidics: Current Status and Future Prospects

Contact Info

Product

Resources

About