Modulating presence and impulsiveness by external stimulation of the brain

Beeli, Gian; Casutt, Gianclaudio; Baumgärtner, Thomas; Jäncke, Lutz

doi:10.1186/1744-9081-4-33

Cited by 124 publications

(100 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The length of the active period of stimulation during the sham session differed between studies, ranging from 5 seconds (Fregni et al 2005;Mylius et al 2012) up to 2 minutes and 45 seconds (Andrews et al 2011;Hoy et al 2013;Hoy et al 2014). However, in 3 studies tDCS was given with a placebo stimulator (Keeser et al 2011;Balconi and Canavesio 2014;Balconi and Vitaloni 2014), while in 1 study, the stimulator was turned off for the entire session (Beeli et al 2008). Regarding blinding, 47 out of the 61 studies were single-blind.…”

Section: Resultsmentioning

confidence: 99%

“…In the remaining 3 studies, the procedure for double blinding was not mentioned (Gill et al 2014;Powell et al 2014;Sela et al 2012). The time period in between the active stimulation session and the sham stimulation session ranged from 3.5 minutes (Beeli et al 2008) to two weeks (Ohn et al 2008). However, there is a large variety in the lengths of IBS.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

The effect of the interval-between-sessions on prefrontal transcranial direct current stimulation (tDCS) on cognitive outcomes: a systematic review and meta-analysis

et al. 2016

View full text Add to dashboard Cite

Recently, there has been wide interest in the effects of transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC) on cognitive functioning. However, many methodological questions remain unanswered. One of them is whether the time interval between active and sham-controlled stimulation sessions, i.e. the Interval Between Sessions (IBS), influences DLPFC tDCS effects on cognitive functioning.Therefore, a systematic review and meta-analysis was performed of experimental studies published in PubMed, Science Direct, and other databases from the first data available to February 2016. Single session shamcontrolled within-subject studies reporting the effects of tDCS of the DLPFC on cognitive functioning in healthy controls and neuropsychiatric patients were included. Cognitive tasks were categorized in tasks assessing memory, attention, and executive functioning. Evaluation of 188 trials showed that anodal vs. sham tDCS significantly decreased response times and increased accuracy, and specifically for the executive functioning tasks, in a sample of healthy participants and neuropsychiatric patients (although a slightly different pattern of improvement was found in analyses for both samples separately). The effects of cathodal vs. sham tDCS (45 trials), on the other hand, were not significant. IBS ranged from less than one hour to up to one week (i.e. cathodal tDCS) or two weeks (i.e. anodal tDCS). This IBS length had no influence on the estimated effect size when performing a meta-regression of IBS on reaction time and accuracy outcomes in all three cognitive categories, both for anodal and cathodal stimulation. Practical recommendations and limitations of the study are further discussed.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

The effect of the interval-between-sessions on prefrontal transcranial direct current stimulation (tDCS) on cognitive outcomes: a systematic review and meta-analysis

et al. 2016

View full text Add to dashboard Cite

show abstract

“…A single session of anodal stimulation over the right PFC showed a slight improvement in attention [55] and working memory [57], while cathodal stimulation led to increased impulsivity [67]. Anodal stimulation of the left posterior parietal lobe led to worsening of performance on working memory [68].…”

Section: Findings In Healthy Subjects and Patientsmentioning

confidence: 98%

“…Montages were also different, with the most common placement situating the two electrodes over the F3 and F4 position on the international 10-20 EEG system. However, the paired electrode location differs across studies with the use of ipsilateral reference electrodes [67,80] or extra-cephalic arm electrodes [54,59,60,81]. These different montages also lead to important differences in the distribution of charge across studies.…”

Section: A Comment On Study Parameters and Designmentioning

confidence: 99%

“…The exact washout period between studies varied, with some studies relying on a washout period of up to 90 min. only [52,67,83] while others relied on a time difference of days to weeks between sessions. The sequence of the sessions also has to be taken into account, as there is evidence that it may impact test performance [84].…”

Section: A Comment On Study Parameters and Designmentioning

confidence: 99%

See 1 more Smart Citation

Transcranial Direct Current Stimulation (tDCS): Modulation of Executive Function in Health and Disease

Sarkis

Kaur

Camprodon

2014

Curr Behav Neurosci Rep

View full text Add to dashboard Cite

Transcranial direct current stimulation (tDCS) is a noninvasive method of neuromodulation used in human basic and clinical neuroscience. In this article we review its use in the cognitive neurosciences to study executive function, and current preliminary explorations of its therapeutic value as a cognitive enhancer for patients with compromised dysexecutive symptoms. We discuss published studies analyzing their methodology and results. A number of experiments describe improvement in experimental measures of inhibitory control, working memory, and verbal fluency with anodal stimulation over the dorsolateral prefrontal cortex. Positive findings are also described in different clinical populations. Despite the growing promise and interest in tDCS given its safety, simplicity, and low cost, findings are not always consistent across studies due to a host of variables we discuss (study design, stimulation parameters, neuroanatomy, genetics, etc.), highlighting the need for a better mechanistic understanding of the effects of tDCS.

show abstract

Online closed‐loop real‐time tES‐fMRI for brain modulation: A technical report

et al. 2022

View full text Add to dashboard Cite

Recent studies suggest that transcranial electrical stimulation (tES) can be performed during functional magnetic resonance imaging (fMRI). The novel approach of using concurrent tES‐fMRI to modulate and measure targeted brain activity/connectivity may provide unique insights into the causal interactions between the brain neural responses and psychiatric/neurologic signs and symptoms, and importantly, guide the development of new treatments. However, tES stimulation parameters to optimally influence the underlying brain activity may vary with respect to phase difference, frequency, intensity, and electrode's montage among individuals. Here, we propose a protocol for closed‐loop tES‐fMRI to optimize the frequency and phase difference of alternating current stimulation (tACS) for two nodes (frontal and parietal regions) in individual participants. We carefully considered the challenges in an online optimization of tES parameters with concurrent fMRI, specifically in its safety, artifact in fMRI image quality, online evaluation of the tES effect, and parameter optimization method, and we designed the protocol to run an effective study to enhance frontoparietal connectivity and working memory performance with the optimized tACS using closed‐loop tES‐fMRI. We provide technical details of the protocol, including electrode types, electrolytes, electrode montages, concurrent tES‐fMRI hardware, online fMRI processing pipelines, and the optimization algorithm. We confirmed the implementation of this protocol worked successfully with a pilot experiment.

show abstract

Modulating presence and impulsiveness by external stimulation of the brain

Cited by 124 publications

References 29 publications

The effect of the interval-between-sessions on prefrontal transcranial direct current stimulation (tDCS) on cognitive outcomes: a systematic review and meta-analysis

The effect of the interval-between-sessions on prefrontal transcranial direct current stimulation (tDCS) on cognitive outcomes: a systematic review and meta-analysis

Transcranial Direct Current Stimulation (tDCS): Modulation of Executive Function in Health and Disease

Online closed‐loop real‐time tES‐fMRI for brain modulation: A technical report

Contact Info

Product

Resources

About