Mohs Micrographic Surgery for the Treatment of Hidradenocarcinoma

Tolkachjov, Stanislav N.; Hocker, Thomas L.; Hochwalt, Phillip C.; Camilleri, Michael; Arpey, Christopher J.; Brewer, Jerry D.; Otley, Clark C.; Roenigk, Randall K.; Baum, Christian L.

doi:10.1097/dss.0000000000000242

Cited by 29 publications

(33 citation statements)

References 31 publications

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“…In a study by Stanislav et al, the authors performed a retrospective review of hidradenocarcinoma patients treated with Mohs micrographic surgery at Mayo clinic from 1993 to 2013 and they found that Mohs micrographic surgery seems to be a useful treatment modality and there was no recurrence, metastasis and disease related mortality in patients treated with Mohs micrographic surgery. 13 In contrary a case report by Lalya et al, they have concluded that adjuvant therapy should be considered postoperatively for improved loco-regional control and should be mandatory in certain histopathological features like dermal lymphatic invasion, perineural invasion, high anaplastic morphology, extracapsular lymph nodal extension, infiltration of deep structures and positive surgical margins. 8 Their patient was initially treated with only surgery and had recurrence within 5 months of surgery and this recurrence was managed successfully by high dose radiotherapy.…”

Section: Discussionmentioning

confidence: 74%

Hidradenocarcinoma of scalp: a case report and review of literature

Gandla

Chatterjee

Patil

et al. 2017

Int J Otorhinolaryngol Head Neck Surg

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<p>Hidradenocarcinoma of the scalp is a rare skin adnexal tumour accounting for less than 0.001% of all tumors. In this study, we describe a rare presentation of the hidradenocarcinoma of the scalp in a 64 years old man. Patient presented with a right side scalp lesion in the occipital area, for which biopsy was done which showed hidradenocarcinoma. Patient underwent wide local excision of the posterior scalp lesion and posterolateral neck dissection and the patient was advised to receive adjuvant chemotherapy and radiotherapy, but the patient refused to undergo adjuvant therapy. Six months postsurgery patient had local recurrence in the posterior margin resection area and lung metastasis, which could have been prevented by adjuvant therapy. Malignant hidradenocarcinoma is a rare aggressive malignant tumour. Patients with this tumour should undergo surgical excision followed by adjuvant therapy.</p>

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Section: Discussionmentioning

confidence: 74%

Hidradenocarcinoma of scalp: a case report and review of literature

Gandla

Chatterjee

Patil

et al. 2017

Int J Otorhinolaryngol Head Neck Surg

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“…Wide surgical excision with at least 2–3 cm has been advocated in some reports. If wide margins cannot be achieved because of anatomical or functional conditions, Mohs micrographic surgery can be used to control a subtle extension of the tumor [ 11 ]. Because of the high tendency for regional lymph node metastasis, prophylactic lymph node dissection has been reported [ 12 ], but this aggressive approach has remained controversial since a long-term benefit has not been clearly demonstrated.…”

Section: Discussionmentioning

confidence: 99%

Malignant Transformation of Nodular Hidradenoma in the Lower Leg

et al. 2018

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Nodular hidradenoma (NH) is a benign adnexal tumor that arises from either eccrine or apocrine sweat glands. NH can originate from any cutaneous site, but the most common sites are the head and anterior surface of the trunk, with very rare cases in the extremities. Long-standing NH has been reported to undergo malignant transformation to malignant NH (MNH); however, its occurrence in the lower leg is extremely rare with only one other case reported to date. In this report, we present a rare case of MNH occurring in the lower leg which was resected with the intent to make a diagnosis. At the final follow-up after 11 months, no local recurrence or metastasis has been observed.

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“…Mohs micrographic surgery has been shown to have superior cure rates in NMSC and is being increasingly used to treat melanoma and other cutaneous malignancies . A complete description of the MMS technique is out of the scope of this article .…”

Section: Discussionmentioning

confidence: 99%