Mohs Surgery for Malignant Eccrine Neoplasms

Wildemore, John K.; Lee, Jason B.; Humphreys, Tatyana R.

doi:10.1111/j.1524-4725.2004.30569.x

Cited by 51 publications

(43 citation statements)

References 34 publications

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“…Clinically, they masquerade as nodular cystic lesion or malignant melanoma. 2 From our case study, it was noticed that constant trauma to skin and connective tissue can lead to transformation of benign adnexal tumour into malignant. This presentation of malignant acrospiroma over scalp is one of the rarest presentation and literature regarding management of such tumour is very limited.…”

Section: Pathological Discussionmentioning

confidence: 86%

A Rare Case of Malignant Acrospiroma Masquerading as Squamous Cell Carcinoma of Scalp

Santosh¹,

Shrikiran²,

Datta³

et al. 2018

jemds

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Section: Pathological Discussionmentioning

confidence: 86%

A Rare Case of Malignant Acrospiroma Masquerading as Squamous Cell Carcinoma of Scalp

Santosh¹,

Shrikiran²,

Datta³

et al. 2018

jemds

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“…The patient was initially started on antibiotics before pathology on the surgically excised digit confirmed malignancy [14]. In other instances, disease masquerades as more common malignant lesions, like malignant melanoma [16]. The other challenge lies in complete sampling of the lesion.…”

Section: Discussionmentioning

confidence: 99%

Malignant acrospiroma: a case report in the era of next generation sequencing

2017

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BackgroundMalignant acrospiroma is a rare tumor of the eccrine sweat glands accounting for around 6% of all malignant eccrine tumors. Typically, it presents as large ulcerated nodules, and diagnosis can be challenging as it has great overlap with its benign counterpart.Case presentationWe herein report a case of acral malignant acrospiroma, initially treated with surgical excision and adjuvant radiotherapy. After metastatic disease was confirmed, subject received multiple lines of chemo- as well as targeted therapy. Genomic testing was also done using next generation sequencing.ConclusionTo the best of our knowledge, this is the first case of acral malignant acrospiroma with reported next generation sequencing results.

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“…As the recurrence rate is high so three monthly follow up is required Mohs micrographic surgery may also be the best option for the clear margins. [5,6] Firstly these tumors were labeled as clear cell papillary carcinomas and there was great diagnostic challenge. This is of poorly circumscribed growth in nature.…”

Section: Discussionmentioning

confidence: 99%

Giant Poroid Submental Hidradenocarcinoma: Radiological Evaluation – Case Report

Sharma¹,

Sharma²,

Bhardwaj³

et al. 2017

AIMDR

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Hidradenocarcinomas are rare tumors of the sweat gland origin and can be of great aggressiveness. These become important entity as these have got high rate of reccurrence, metastasis and the management is not encouraging. There may be pre existing adenoma from which these tumors develop without producing any alarming symptomatology. The causative factor is still unknown. We present 54-years old male who presented with huge submental swelling without much of the complaints except cosmetically and that of huge mass. The patient was subjected to cross sectional imaging by contrast enhanced computerized tomography (CECT) and contrast enhanced magnetic resonance imaging (CEMRI).The diagnosis remained inconclusive before surgery. The patient underwent total surgical excision and histopathologically was diagnosed as hidradenicarcinoma.

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Mohs Surgery for Malignant Eccrine Neoplasms

Abstract: While the clinical experience is limited, the use of MMS appears to decrease recurrence rates when compared to conventional surgical excision. Further experience and longer follow-up intervals will be necessary to demonstrate superior efficacy and recommended surgical margins.

Cited by 51 publications

References 34 publications

A Rare Case of Malignant Acrospiroma Masquerading as Squamous Cell Carcinoma of Scalp

A Rare Case of Malignant Acrospiroma Masquerading as Squamous Cell Carcinoma of Scalp

Malignant acrospiroma: a case report in the era of next generation sequencing

Giant Poroid Submental Hidradenocarcinoma: Radiological Evaluation – Case Report

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