Molecular Alterations Associated with Histologically Overt Stromal Response in Patients with Prostate Cancer
Mutlay Sayan,
Yetkin Tuac,
Mahmut Akgul
et al.
Abstract:Prostate cancer has substantial heterogeneity in clinical outcomes and therapeutic responses, posing challenges in predicting disease progression and tailoring treatment strategies. Recent studies have highlighted the potential prognostic value of evaluating the tumor microenvironment, including the presence of a histologically overt stromal response (HOST-response) characterized by peri-glandular stromal changes and architectural distortions. This retrospective study examined patient records from The Cancer G… Show more
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