Molecular analyses on the genetic diversity and inheritance of (−)-α-bisabolol and chamazulene content in tetraploid chamomile (Chamomilla recutita (L.) Rausch.)

Wagner, Carola; Friedt, W.; Marquard, R.; Ordon, Frank

doi:10.1016/j.plantsci.2005.06.010

Cited by 29 publications

(27 citation statements)

References 31 publications

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“…Indeed, it is an artefact molecule obtained from the precursore prochamazulene contained in plants' tissues [18,46] during steam distillation. Chamazulene possesses interesting anti-inflammatory properties [41], and for this reason it has a relevant industrial importance.…”

Section: Discussionmentioning

confidence: 99%

Chemical Composition and Antibacterial Potential of Artemisia arborescens L. Essential Oil

et al. 2010

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This study was undertaken to characterize the essential oil (EO) of Artemisia arborescens growing wild in Sicily. EO, extracted by steam distillation, was examined for its chemical composition and for its capability to inhibit some food-borne pathogen bacteria. A total of 43 compounds (13 monoterpene hydrocarbons, 14 oxygenated monoterpenes, 10 sesquiterpene hydrocarbons, three oxygenated sesquiterpenes and less amount of other three compounds), which account 93.73% of the total oil, were identified by gas chromatography and gas chromatography-mass spectrometry. Oxygenated monoterpenes (57.32%) constituted the main fraction, with b-thujone as the main compound (45.04%), followed by the sesquiterpene hydrocarbon chamazulene (22.71%). Undiluted EO showed a large inhibition spectrum against strains of Listeria monocytogenes (34 out of 44), whilst it was ineffective against enterobacteria and salmonellas. The minimum inhibition concentration (MIC) was evaluated for the two most sensitive strains (L. monocytogenes 186 and 7BO) at two cellular concentrations (10 6 and 10 7 CFU ml -1 ). The lowest MIC (0.625 ll ml -1 , dilution of oil with acetone) was found for strain L. monocytogenes 186 at 10 6 CFU ml -1 .

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Section: Discussionmentioning

confidence: 99%

Chemical Composition and Antibacterial Potential of Artemisia arborescens L. Essential Oil

et al. 2010

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“…Within the species M. chamomilla, a chemical polymorphism regarding essential oil composition was first shown by Schilcher [9] and has been substantiated by several studies [10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 92%

Biological Activity of Matricaria chamomilla Essential Oils of Various Chemotypes

Höferl

Wanner²,

Tabanca³

et al. 2020

Planta Medica International Open

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The essential oil of Matricaria chamomilla L., which is commonly used for medicinal and cosmetic purposes, can be differentiated between several chemotypes. In the current study, six essential chamomile oil samples of various origins (four of commercial sources, one of cultivation, one of wild collection) were examined regarding their composition and biological activities, i. e., antibacterial, antifungal, mosquito repellent, and larvicidal effects. GC-MS analyses revealed that the samples largely varied in composition and could be attributed to various chemotypes. In contrast to the other two samples, the four commercial samples were unusually high in trans-β-farnesene. The overall antimicrobial effects were only moderate, but it could be shown that a higher content in α-bisabolol and a smaller in α-bisabolol oxides A and B had a positive effect on overall activity. All samples had a biting deterrent effect comparable to DEET. Higher concentrations of (Z )- and (E )-spiroethers improved larvicidal activity, whereas trans-β-farnesene had the opposite effect. In conclusion, the importance of α-bisabolol for the biological activity of chamomile essential oil could be demonstrated.

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“…Significant success was achieved in isolation and characterization of several structural genes related to flavonoid biosynthetic pathway in gentian (Nakatsuka et al 2005(Nakatsuka et al , 2008Shimada et al 2009). Furthermore, segregation analysis of F2-individuals of chamomile revealed a monogenic recessive mode of inheritance of the (À)-α-bisabolol and chamazulene content, whereas by bulked segregant analysis three AFLP-markers linked to the (À)-α-bisabolol locus and one RAPD and 17 AFLP markers for the chamazulene content were detected, suggesting that the markers for the chamazulene content could be suited for pre-flowering marker based selection procedures (Wagner et al 2005). Pank (2002) reported that focus of breeding research in medicinal plants arise mostly in the fields of pharmacology, genetics, breeding methodology, reproductive biology, pathogen diagnostic, development of initial material for breeding, rationalization of trait determination methods, hybrid creation and biotechnology in general.…”

Section: Challenges and Current Approaches In Selection And Breeding mentioning

confidence: 95%

“…For efficient plant breeding, knowledge on the genetic diversity within adapted germplasms and the relatedness of potential parental lines, as well as detailed information on the mode of inheritance of the trait of interest, is a prerequisite (Wagner et al 2005). Mapping of genes and specific DNA sequences involved in biosynthesis of particular metabolite classes seem to be future challenge in MAP breeding programs.…”

Section: Challenges and Current Approaches In Selection And Breeding mentioning

confidence: 99%

Challenges and Decision Making in Cultivation of Medicinal and Aromatic Plants

Dajić-Stevanović

Pljevljakušić

2015

Medicinal and Aromatic Plants of the World

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Cultivation of medicinal and aromatic plants (MAP) today is not only a promising alternative and counterpoint to wild collection, enabling preservation of natural genetic variability and survival of rare, endemic, vulnerable and endangered species, but also represents a powerful economy branch providing the high class quality raw material for pharmaceutical, cosmetic and the food industry. Domestication and cultivation of most of medicinal plants, usually conceived as a minor crops, face with many challenges on small, medium and large scale production, relating both cultivation technologies and market and prices fluctuations. Cultivated MAP material is increasingly preferred by the herbal industry, because it is easier to predict plant yield, quality and drug composition, especially when compared with wild harvested raw materials. In case of cultivated MAP material, the possibility of plant misidentification and adulteration is excluded. The profitability of cultivation of medicinal plants compete with profit achievable for standard field crops for which already exist a specialized machinery and a standard procedure for application of fertilizers and agrochemicals to control weeds, pests and diseases. For successful large scale cultivation of MAP, the high quality raw material should be produced using low input cultivation methods to be competitive at the international market and with plants collected from the wild. The most common issues with which the producers of medicinal plants encountered are the market, abundance and accessibility of wild populations, agro-environmental conditions, labor availability and costs, investments in machinery, post-harvest processing, and profitability of production. Superior genotypes are very important for profitable production of the high quality medicinal plants' row material. Out of all cultivated medicinal plant species, only a small percentage is clearly genetically defined and represented on the seed market in term of variety. Similarly to the other crops, traditional breeding methods, as well as biotechnological procedures and selection assisted by molecular markers are applied in development of new varieties and Mapping of genes and specific DNA sequences involved in biosynthesis of particular metabolite classes seems to be a future challenge in MAP breeding programs. Most of actual research is focused on genetic variability among different taxa of medicinal plants using several types of DNA markers, including restriction fragment length polymorphism (RFLP), amplified fragment length polymorphic DNA (AFLP), random amplified polymorphic DNA (RAPD), cleavage amplified polymorphic sequence (CAPS), simple sequence repeat (SSR), and sequence characterized amplified region (SCAR) markers. Although the primary target for trait manipulation in medicinal plants is the content of active compounds, for development as crops, basic agronomic characters related to uniformity, stability, growth and development, and resistance to biotic and abiotic stresses, must also be impro...

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Molecular analyses on the genetic diversity and inheritance of (−)-α-bisabolol and chamazulene content in tetraploid chamomile (Chamomilla recutita (L.) Rausch.)

Cited by 29 publications

References 31 publications

Chemical Composition and Antibacterial Potential of Artemisia arborescens L. Essential Oil

Chemical Composition and Antibacterial Potential of Artemisia arborescens L. Essential Oil

Biological Activity of Matricaria chamomilla Essential Oils of Various Chemotypes

Challenges and Decision Making in Cultivation of Medicinal and Aromatic Plants

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