“…Among them, Vibrio is recognized as one of the most harmful diseases in marine fish culture. As a Gramnegative bacterium, V. alginolyticus is an important conditional pathogen and has caused significant economic losses in the mariculture industry (Chen et al, 2010;Lim et al, 2021). To investigate the effect of CPC substitution for fishmeal and tributyrin on the disease resistance of hybrid grouper, we conducted a 1-week challenge test using V. alginolyticus and found that CPC significantly reduced the survival of hybrid grouper, and supplementation with strains, and this effect is closely related to the dose of organic acids (Chuchird et al, 2015).…”