Phys. Chem. Chem. Phys.
 2023
DOI: 10.1039/d2cp05968a
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Molecular dynamic simulations identifying the mechanism of holoenzyme formation byO-GlcNAc transferase and active p38α

Yu Wang
1
,
Zhiyang Zhang
2
,
Xiaoyuan Liu
3
et al.

Abstract: O-N-acetylglucosamine transferase (OGT) can catalyze the O-GlcNAc modification of thousands of proteins. The holoenzyme formation of OGT and adaptor protein is the precondition for the further recognition and glycosylation of...

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