Molecular Engineering to Enhance Aptamer Functionality

Abstract

Rapid development of bioanalysis and biomedicine requires enhanced and multiple functionality of aptamers. The field of molecular engineering has advanced to a stage where more and more molecular functions can be rationally designed in a predictable manner. By combining these two fields together, aptamerbased molecular engineering is able to tune the functionalities of aptamers toward more complicated and effective biological and biomedical applications. In this chapter, we focus on introducing the substantial progress in the development of using smart ways to broaden the multifunctional and logical applications of aptamers.