Molecular filters based on cyclodextrin functionalized electrospun fibers

Uyar, Tamer; Havelund, Rasmus; Nur, Yusuf; Hacaloğlu, Jale; Besenbacher, Flemming; Kingshott, Peter

doi:10.1016/j.memsci.2009.01.047

Cited by 110 publications

(91 citation statements)

References 37 publications

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“…Moreover, in order to combine the complex formation capability of CD along with very high surface area of the electrospun nanofibrous mat, surface functionalization of electrospun nanofibers with CD would be quite interesting for designing efficient filtering materials. In fact, in our recent studies we have incorporated CD into nanofibers by electrospinning of physical mixture of polymer/CD solution [4,22,23]. Although most of the CD molecules were buried inside the fiber matrix, we observed that some CD molecules were present on the fiber surface, and these surface associated CD molecules were effective for the removal of organic molecules from liquid media [22,23] and vapor phase [4].…”

Section: Introductionmentioning

confidence: 87%

“…The increase in oxygen content of PET/CDP nanofibers compared to unmodified PET nanofibers was especially due to the appearance of C O * H for the samples. The presence of CDP on the fiber surface is quite important in terms of the filtration application of PET/CDP nanofibrous mats [4,22,23].…”

Section: Surface Chemical Characterization Of the Nanofibersmentioning

confidence: 99%

“…In fact, in our recent studies we have incorporated CD into nanofibers by electrospinning of physical mixture of polymer/CD solution [4,22,23]. Although most of the CD molecules were buried inside the fiber matrix, we observed that some CD molecules were present on the fiber surface, and these surface associated CD molecules were effective for the removal of organic molecules from liquid media [22,23] and vapor phase [4]. However, CD molecules were physically attached to the fiber surface; so, the leaching of CD molecules from the fiber surface during filtration especially in the liquid media was inevitable.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Surface modification of electrospun polyester nanofibers with cyclodextrin polymer for the removal of phenanthrene from aqueous solution

Kayacı

Aytaç

Uyar

2013

Journal of Hazardous Materials

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132

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Cataloged from PDF version of article.Surface modified electrospun polyester (PET) nanofibers with cyclodextrin polymer (CDP) were produced (PET/CDP). CDP formation onto electrospun PET nanofibers was achieved by polymerization between citric acid (CTR, crosslinking agent) and cyclodextrin (CD). Three different types of native CD (α-CD, β-CD and γ-CD) were used to form CDP. Water-insoluble crosslinked CDP coating was permanently adhered onto the PET nanofibers. SEM imaging indicated that the nanofibrous structure of PET mats was preserved after CDP surface modification process. PET/CDP nanofibers have shown rougher/irregular surface and larger fiber diameter when compared to untreated PET nanofibers. The surface analyses of PET/CDP nanofibers by XPS elucidated that CDP was present on the fiber surface. DMA analyses revealed the enhanced mechanical properties for PET/CDP where PET/CDP nanofibers have shown higher storage modulus and higher glass transition temperature compared to untreated PET nanofibers. The surface area of the PET/CDP nanofibers investigated by BET measurements showed slight decrease due to the presence of CDP coating compared to pristine PET nanofibers. Yet, it was observed that PET/CDP nanofibers were more efficient for the removal of phenanthrene as a model polycyclic aromatic hydrocarbon (PAH) from aqueous solution when compared to pristine PET nanofibers. Our findings suggested that PET/CDP nanofibers can be a very good candidate as a filter material for water purification and waste treatment owing to their very large surface area as well as inclusion complexation capability of surface associated CDP

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Section: Introductionmentioning

confidence: 87%

Section: Surface Chemical Characterization Of the Nanofibersmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Surface modification of electrospun polyester nanofibers with cyclodextrin polymer for the removal of phenanthrene from aqueous solution

Kayacı

Aytaç

Uyar

2013

Journal of Hazardous Materials

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132

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“…In our previous studies, we have demonstrated that CD functionalized polymeric NF can be potentially used as molecular filters for the air and water filtration by removing organic molecules from the required environment (Kayaci et al, 2013;Kayaci and Uyar, 2014;Uyar et al, 2009Uyar et al, , 2010aUyar et al, , 2010b. The integration of polymeric NF with CD, facilitated the entrapment property of nanofibrous webs owing to the complexation capability of CD molecules located on the fiber surface (Kayaci et al, 2013;Kayaci and Uyar, 2014;Uyar et al, 2009Uyar et al, , 2010aUyar et al, , 2010b. Furthermore, in our very recent study, we eliminated the polymer matrix and we have shown that the polymer-free γ -CD NF can also efficiently encapsulate aniline and toluene vapor from the environment depending on the inclusion complexation so these nanofibrous webs have great potential to be used as a molecular filter (Celebioglu and Uyar, 2013b).…”

Section: Vocs Entrapment Capability Of CD Nf and Cd Powdermentioning

confidence: 99%

Molecular entrapment of volatile organic compounds (VOCs) by electrospun cyclodextrin nanofibers

et al. 2016

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In this paper, we reported the molecular entrapment performance of hydroxypropyl-beta-cyclodextrin (HPβCD) and hydroxypropyl-gamma-cyclodextrin (HPγCD) electrospun nanofibers (NF) for two common volatile organic compounds (VOCs); aniline and benzene. The encapsulation efficiency of CD samples were investigated depending on the various factors such as; CD form (NF and powder), electrospinning solvent (DMF and water), CD (HPβCD and HPγCD) and VOCs (aniline and benzene) types. BET analysis indicated that, electrospun CD NF have higher surface area compared to their powder form. In addition DMA measurement provided information about the mechanical properties of CD NF. The encapsulation capability of CD NF and CD powder was investigated by 1H-NMR and HPLC techniques. The observed results suggested that, CD NF can entrap higher amount of VOCs from surroundings compared to their powder forms. Besides, molecular entrapment efficiency of CD NF also depends on CD, solvent and VOCs types. The inclusion complexation between CD and VOCs was determined by using TGA technique, from the higher decomposition temperature of VOCs. Finally, our results were fortified by the modeling studies which indicated the complexation efficiency variations between CD and VOC types. Here, the inclusion complexation ability of CD molecules was combined with very high surface area and versatile features of CD NF. So these findings revealed that, electrospun CD NF can serve as useful filtering material for air filtration purposes due to their molecular entrapment capability of VOCs. © 2015 Elsevier Ltd

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“…In particular, a chemically modified CD like HP␤CD is more suitable for the solubilization of hydrophobic drugs, because of its better aqueous solubility compared to native CDs [11]. It has been shown that CDs and CD-ICs can be used in functionalization of electrospun nanofibers for different applications like biomedical [12][13][14][15][16][17], filtration [18][19][20] and food packaging [21][22][23][24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Sulfisoxazole/cyclodextrin inclusion complex incorporated in electrospun hydroxypropyl cellulose nanofibers as drug delivery system

Aytaç

Sen

Durgun

et al. 2015

Colloids and Surfaces B: Biointerfaces

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106

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a b s t r a c tHerein, hydroxypropyl-beta-cyclodextrin (HP␤CD) inclusion complex (IC) of a hydrophobic drug, sulfisoxazole (SFS) was incorporated in hydroxypropyl cellulose (HPC) nanofibers (HPC/SFS/HP␤CD-IC-NF) via electrospinning. SFS/HP␤CD-IC was characterized by DSC to investigate the formation of inclusion complex and the stoichiometry of the complex was determined by Job's plot. Modeling studies were also performed on SFS/HP␤CD-IC using ab initio technique. SEM images depicted the defect free uniform fibers and confirmed the incorporation of SFS/HP␤CD-IC in nanofibers did not alter the fiber morphology. XRD analyses showed amorphous distribution of SFS/HP␤CD-IC in the fiber mat. Release studies were performed in phosphate buffered saline (PBS). The results suggest higher amount of SFS released from HPC/SFS/HP␤CD-IC-NF when compared to free SFS containing HPC nanofibers (HPC/SFS-NF). This was attributed to the increased solubility of SFS by inclusion complexation. Sandwich configurations were prepared by placing HPC/SFS/HP␤CD-IC-NF between electrospun PCL nanofibrous mat (PCL-HPC/SFS/HP␤CD-IC-NF). Consequently, PCL-HPC/SFS/HP␤CD-IC-NF exhibited slower release of SFS as compared with HPC/SFS/HP␤CD-IC-NF. This study may provide more efficient future strategies for developing delivery systems of hydrophobic drugs.

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Molecular filters based on cyclodextrin functionalized electrospun fibers

Cited by 110 publications

References 37 publications

Surface modification of electrospun polyester nanofibers with cyclodextrin polymer for the removal of phenanthrene from aqueous solution

Surface modification of electrospun polyester nanofibers with cyclodextrin polymer for the removal of phenanthrene from aqueous solution

Molecular entrapment of volatile organic compounds (VOCs) by electrospun cyclodextrin nanofibers

Sulfisoxazole/cyclodextrin inclusion complex incorporated in electrospun hydroxypropyl cellulose nanofibers as drug delivery system

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