Abstract. We will begin with a simplified view of systems biology and synthetic biology. Systems biology extracts information from life, while synthetic biology converts information to reality. This cycle allows the coevolution of life and information, and accelerates the evolution of both. Additionally, the field of molecular robotics has recently emerged. This field is attempting to implement artificial life using biological molecules. We foresee that molecular robots will interface information and life, and the distinction among information, life and artificial life will eventually become a blur. Once molecular robots gain the ability to evolve, then co-evolution of the three will lead to a new stage of intelligence.