Molecular Segregation at Periodic Metal Nano‐Architectures on a Solid Surface

Nabika, Hideki; Murakoshi, Kei

doi:10.1002/9783527627820.ch13

Cited by 1 publication

(2 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2). [23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42] The formation of a highly localized compressed phase at the gates acts as the electrochemical potential barrier for the incorporated dye-labeled lipids. The potential barrier reduces the passing ability of dye lipids through the gate, leading to the emergence of the molecular filtering phenomenon.…”

Section: Manipulation Of a Small Number Of Molecules In Self-mentioning

confidence: 99%

“…The present result that the horn-shaped geometry (gate width = 100 nm) caused a higher ratchet effect than the normal geometry (gate width = 250 nm) is reasonable, because the molecular filtering effect is known to be enhanced when using metallic channel-shaped width. 42 In our ratchet experiment, the filtering effect should be more obvious on the channel-shaped ratchet obstacles than on the horn-shaped Electrochemistry, 82(9), 712-719 (2014) ratchet obstacles. An increment in the retention time of molecules at the gates leads to the highest separation angle at channel-shaped obstacles.…”

Section: Manipulation Of a Small Number Of Molecules In Self-mentioning

confidence: 99%

See 1 more Smart Citation

Molecule Manipulation at Electrified Interfaces using Metal Nanogates

et al. 2014

Self Cite

View full text Add to dashboard Cite

Previously documented results on molecule manipulation using metal nanogates are comprehensively reviewed to conclude novel characteristics, which could be widely used for the developments of the systems at electrified interfaces. Novel systems to segregate molecules from self-spreading lipid bilayers in electrolyte solutions have been developed by using metal nanogate structures on solid surfaces. The spatial distribution of target molecules in the lipid bilayer changes depending on the molecule characteristics, such as charge, size, and flexibility. Energy dissipation during the spreading of the molecules on the surface contributes to the compression of the lipid bilayer at the nanogate, leading to the formation of a gradient of the electrochemical potential of the bilayer system including the target molecule in the vicinity of the nanogate (<100 nm from the gate). The gradient results in a segregation force being applied to target molecules in the order of 10 −15 N per molecule. The segregation property can be tuned by changing the electrolytes, lipid molecules, temperature, and the width and surface hydrophobicity of the metal nanogate. Introduction of asymmetry to the nanogate leads to further effective diffusion control in a direction perpendicular to the spreading. It has been demonstrated that target molecules with a different number of glycolipid per protein in the lipid bilayer are effectively separated based on the Brownian ratchet mechanism.

show abstract