Molecularly imprinted miniature electrochemical biosensor for SARS-CoV-2 spike protein based on Au nanoparticles and reduced graphene oxide modified acupuncture needle

A surface molecularly imprinted electrochemical biosensor for the detection of SARS-CoV-2 spike protein by using Cu7S4-Au as built-in probe

“…The analytical performances of the as-fabricated SMI biosensor are also compared with other SARS-CoV-2-S protein biosensors previously reported [6] , [35] , [38] , [39] , [40] , [41] , and the results are listed in Table 1 . Obviously, the developed SMI biosensor is far superior to the previous SARS-CoV-2-S protein biosensors in terms of both linear range and LOD.…”

Introductory Chapter: Current Landscape of Animal and Human Virus Treatments

“…It has been applied in animal viruses with nanoparticle deployment, such as with African Swine Fever Virus (ASFV) [47,48]. Moreover, it is also trialed in detecting SARS-CoV-2 as well [49]. Despite the development of alternatives, WHO has not changed its stance pertaining to its virology SOPs.…”

A mesothelin microsensor based on an embedded thionine electronic medium within an imprinted polymer on an acupuncture needle electrode

“…Then, the MSLN protein template was eluted with 0.1 M PBS ( pH = 5.0) containing 5% (v/v) methanol for 2 h to obtain a molecularly imprinted microsensor, which was denoted as ANE/AuNPs ∼ 4-MPBA ∼ MSLN/pTH/pEBT/MIP. 28 For the control experiment, a non-imprinted microsensor (ANE/AuNPs ∼ 4-MPBA/pTH/ pEBT/NIP) was also prepared using the same procedure without the addition of the MSLN protein template.…”