Molecularly imprinted polymer-based potentiometric sensor for degradation product of chemical warfare agentsPart I. Methylphosphonic acid

Imprinted Polymer Inclusion Membrane Based Potentiometric Sensor for Determination and Quantification of Diethyl Chlorophosphate in Natural Waters

“…The plasticizer NPOE having a high dielectric constant of 24.0 has given better response characteristics than that of DOP ( ε = 5.0), BEHS ( ε = 4.0) and TEHP ( ε = 4.8). This is in agreement with earlier reports [20,21]. It was also observed that the imprinted membranes casted without plasticizer were not suitable for use as recognition membranes as they are brittle.…”

“…The recovery studies of DCP from ground and river waters indicated the possibility of using the sensor investigated in the present work for nature water samples. The developed technology found to be a effective analytical tool as it requires simple sample preparation procedures and does not require large instrumentation as it is a miniature device that responds to a particular analyte in a selective way and can be effectively used for the determination of pollutants in the environmental and biological samples [20,23]. Further studies are in progress to integrate other transducers with MIP materials for a chosen template.…”

“…The previous studies [22] had succeeded in construction of semi-covalent strategy based in-situ monolithic polymer membrane based sensor for DCP via single pot synthesis. The extraction of all possible degradation products of the chemical warfare agents using molecularly imprinted polymers were developed by various research groups [20,23,24]. The semi-covalent strategy has been successfully demonstrated in the present study for the fabrication of imprinted polymer inclusion membrane (IPIM) based sensor for the detection and quantification of DCP, a simulant of soman present in spiked natural waters.…”

“…Zhou, et al [19] reported for the first time MIP based potentiometric sensor for methylphosphonic acid, an ultimate degradation product of nerve agents by coupling surface imprinting technique with a nanoscale transducer, indium tinoxide. The literature reveals that the prepared imprinted polymer membranes can be effectively used for the detection of nerve agents by fabricating them into potentiometric sensors [19][20][21]. These sensing devices are essentially based on use of polymer materials prepared via non-covalent strategy.…”

Synthesis by precipitation polymerization of a molecularly imprinted polymer membrane for the potentiometric determination of sertraline in tablets and biological fluids

“…Despite the relatively simple transduction of the potentiometric signal, only limited reports on the design of the potentiometric sensors have been based on the molecular imprinting technology. These reports describe the dispersion of the MIP particles in the plasticizer and their embedment in a polyvinylchloride (PVC) matrix, [18][19][20][21] the formation of a glassy membrane, 22 the template assembly on the polar surface of the indium tin oxide (ITO) glass plate 23,24 and the deposition of an MIP polymeric film on the gate surface of an ion-sensitive field-effect transistor. 25,26 The prescription of new antidepressant drugs has increased dramatically in the last few years.…”