1985
DOI: 10.1002/ange.19850971204
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Molekulare Wirkungsweise des Antibioticums Rifampicin

Abstract: Die Titelseite zeigt zwei Carbolegerlinge (Agaricus xanthoderma)Bei der Weitergahe der genetischen Information und ihrer Umsetzung in Proteinsequenzen mulj eine hohe Genauigkeit gewahrleistet sein. In vielen Fallen ist eine ausreichende Genauigkeit nicht allein aufgrund der unterschiedlichen Bindungsenergien des richtigen und des falschen Substrats zu erzielen, sondern erfordert einen zusatzlichen Pruf-und gegebenenfalls Korrekturschritt. Dabei wird eine als falsch erkannte Zwischenstufe enzymatisch hydrolysie… Show more

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Cited by 3 publications
(1 citation statement)
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“…However, they are also active against some gram-negative bacteria and many viruses. They form a class of antibiotics with a specific potency as drug against tuberculosis via inhibition of the DNA-dependent RNA polymerase [3]. Rifamycin SV (which lacks a C-4 constituent) and the glycolic acid linked at C-3 has antibacterial activity.…”
Section: Introductionmentioning
confidence: 99%
“…However, they are also active against some gram-negative bacteria and many viruses. They form a class of antibiotics with a specific potency as drug against tuberculosis via inhibition of the DNA-dependent RNA polymerase [3]. Rifamycin SV (which lacks a C-4 constituent) and the glycolic acid linked at C-3 has antibacterial activity.…”
Section: Introductionmentioning
confidence: 99%