Monitoramento de gestantes com toxoplasmose em serviços públicos de saúde

Abstract

RESUMOÉ discutido o monitoramento de 290 gestantes com suspeita de toxoplasmose aguda atendidas em serviços públicos. Em 69% um único teste (ELISA-IgM) conduziu ao tratamento. De 112 tratadas, o sistema não disponibilizou medicamento para 24%. Em 12,1% houve aumento progressivo de IgM e IgG. Em 48,2%, o tratamento foi iniciado trinta dias após o diagnóstico laboratorial. Palavras-chaves: Gestantes. Toxoplasmose. Pré-natal. Monitoramento. ABSTRACTThe monitoring of 290 pregnant women with suspicion of acute toxoplasmosis attended by Public Health Services is discussed. In 69% a single test (ELISA-IgM) led to the treatment. Of 112 treated, the system did not offer any drug to 24%. In 12.1% there was a progressive increase of IgM and IgG. In 48.2% the treatment was begun thirty days after the laboratorial diagnosis.

Anti-Toxoplasma gondii antibodies in pregnant women and their newborn infants in the region of São José do Rio Preto, São Paulo, Brazil

“…Since the avidity indexes were identical to those of the maternal serum and the methods used in this study were unable to differentiate IgG antibodies from mothers and babies, it can be assumed of the fetuses can become infected. 13,14,16 The fetuses of these two pregnant women were probably not infected during gestation, although this condition is not conclusive. There have been reports that 70% of newborns infected during gestation do not present symptoms at birth.…”

“…10 Additionally, Brazilian studies have demonstrated that infection rates among pregnant women vary according to the geographical region. [10][11][12][13][14][15][16] However, there are only a few studies evaluating anti-T. gondii antibodies and their avidity in mothers and their newborns in the state of For ELISA, the crude extract of tachyzoites was obtained as previously described. 21 The parasites were sonicated (10 cycles of 1.0 A/minute for five minutes with two-minute intervals).…”

Factors associated to infection by Toxoplasma gondii in pregnant women attended in Basic Health Units in the city of Rolândia, Paraná, Brazil

“…The importance of implanting maternal serum screening to detect toxoplasmosis lies in the possibility of adopting prophylactic and therapeutic measures to minimize the vertical transmission and/or decrease the damage to fetus development 15 . In the face of the seriousness of the congenital disease, it is fundamental to start prenatal care in the first three months of pregnancy, so that, acute cases of congenital toxoplasmosis can be early identified 40 .…”

Programas de controle da toxoplasmose congênita

“…The maternal serum screening for detection of toxoplasmosis is an important tool, which allows the adoption of early prophylactic and therapeutic measures, thus reducing the rate of vertical transmission and/or fetal development impairment 18 . Therefore, it is essential to start the prenatal care in the first trimester of pregnancy, performing the serological screening, allowing the early identification of acute cases of gestational toxoplasmosis 19 .…”