Monkeypox and human transmission: Are we on the verge of another pandemic?

Farahat, Ramadan Abdelmoez; Ali, Iftikhar; Al-Ahdal, Tareq; Benmelouka, Amira Yasmine; Albakri, Khaled; El-Sakka, Amro A; Abdelaal, Abdelaziz; Abdelazeem, Basel; Anwar, Mohammed Moustapha; Mehta, Rachana; Sah, Ranjana; Rouniyar, Ramhari; Sah, Ranjit

doi:10.1016/j.tmaid.2022.102387

Cited by 27 publications

(16 citation statements)

References 17 publications

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“…The diffusion of monkeypox in several countries outside Africa is a major public health concern. Although it is quite unlikely that this outbreak will reach the proportion of a pandemic [ 42 ], several regions such as Central and Western Europe have been declared at a high risk and monkeypox has also become a public health concern in high-income countries [ 8 ]. Therefore, concerns are raising about the safety of workers that may be occupationally exposed to the virus, especially in light of the lessons learned from COVID-19 [ 43 ].…”

Section: Discussionmentioning

confidence: 99%

Prevention, Risk Exposure, and Knowledge of Monkeypox in Occupational Settings: A Scoping Review

et al. 2022

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With ongoing climate change, which alters the conditions for pathogens and vectors, zoonotic diseases such as monkeypox virus will become a challenge and a great threat impacting global health in future decades. A current outbreak of monkeypox is occurring in over 125 countries, with a report of thousands of cases in countries where this virus has never appeared. Occupational exposure to the monkeypox virus has recently been identified as an issue of major concern for occupational health, especially in healthcare settings. A scoping review following the PRISMA guidelines was performed, aiming to analyze the effects that the current monkeypox outbreak has in workplaces, given the potential exposure of healthcare workers to the virus, the possible spread of the virus in occupational settings, and the preventive measures that are necessary to implement. At the end of the selection process, 21 studies were included in the review. Healthcare workers are considered at a high risk, and similar preventive measures to those adopted during the SARS-CoV-2 pandemic must be implemented in all healthcare settings. The main recommendations for preventing and managing monkeypox in occupational settings are the vaccination of exposed workers, the prompt identification and isolation of infected individuals, and good hygiene practices. Education and specific training are necessary in non-endemic countries to make healthcare workers able to recognize the disease and prevent further contagions. Although monkeypox seems unlikely to reach the pandemic spread of COVID-19, an approach to global health even to avoid future zoonotic epidemics is required by all stakeholders.

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Section: Discussionmentioning

confidence: 99%

Prevention, Risk Exposure, and Knowledge of Monkeypox in Occupational Settings: A Scoping Review

et al. 2022

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“…Moreover, the coinfection of MPX and syphilis have been reported in HIV patients (Bízova et al 2022). It is highly recommended to investigate the possibility of a combination of MPX with COVID-19 or other diseases which might be dangerous and may increase the fatalities (Farahat et al 2022).…”

Section: Public Health Threatsmentioning

confidence: 99%

Monkeypox: An Update on Current Knowledge and Research Advances

Chandran¹,

Dhama

Aslam

et al. 2022

J Exp Bio & Ag Sci

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The resurgence of the disease in humans that is very similar to smallpox called monkeypox (MPX) disease, caused by the monkeypox virus (MPXV), is the dominant topic of discussion in the scientific and popular press around the world right now. This is taking place as the world celebrates the historic accomplishments made in the fight against the Coronavirus Disease (COVID-19) pandemic MPX is currently thought to pose a risk to the general public's health, particularly in areas with high rates of MPXV infection and close human-wild animal contact. Despite the rarity of MPX outbreaks, they are often caused by human-to-human transmission, especially in households and healthcare settings. Recent decades have seen recurrent outbreaks of the MPX after the smallpox disease was declared eliminated and the consequent cessation of smallpox vaccination programs. MPX has presently spread to several countries throughout the world and posed a global public health emergency, with nearly 45000 confirmed cases in 96 countries and locations, and 12 deaths as of August 24, 2022. Even though this viral illness is thought to be self-limiting, its consequences and feasible pandemic potential seriously jeopardize public health. The main approach to avoiding MPX is to adopt appropriate prevention and control measures, increase awareness of risk factors, and inform the public of the steps they may take to reduce viral exposure. Scientific studies are currently looking at the viability and suitability of the MPX vaccination. This article presents a general introduction to MPXV / MPX along with progress in diagnosis, treatment, vaccination, and prevention and control strategies for tackling this global health emergency.

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“…Scientists and researchers fight against the diseases from clinical applications to fundamental aspects such as diagnosis, clinical therapy, vaccination, immunology, and virology, and the research outcomes are reflected and displayed in publications. The analysis of publications, called bibliometrics, is broadly used to quantitatively investigate scientific research [ 2 ]. Bibliometrics has been reported to be helpful in enabling an objective evaluation of scientific research and presenting relevant research hotspots [ 3 , 4 ].…”

mentioning

confidence: 99%