Monkeypox claims new victims: the outbreak in men who have sex with men

Liu, Xiaoning; Zhu, Zheng; He, Ying; Lim, Jia Wen; Lane, Bethany F; Wang, Hui; Peng, Qingsheng; Sun, Liqin; Lu, Hongzhou

doi:10.1186/s40249-022-01007-6

Cited by 56 publications

(55 citation statements)

References 7 publications

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“…In Italy, the number of cases increased during the last week of July [ 22 ]. This recent multinational outbreak of Monkeypox cases has revealed a changing epidemiological trend, with a high proportion of cases occurring among MSM, reaching 87% in Spain [ 28 , 29 ]. Of the eight male patients described in the present study, six (75%) were MSM.…”

Section: Discussionmentioning

confidence: 99%

Monkeypox Virus Infections in Southern Italy: Is There a Risk for Community Spread?

Loconsole

Sallustio

Centrone

et al. 2022

IJERPH

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The ongoing outbreak of the Monkeypox virus (MPXV) is characterized by sustained human-to-human transmission, particularly among men who have sex with men (MSM). The aim of the study was to describe the characteristics of the MPXV infection identified in Southern Italy. Clinical samples for each suspected case identified from 1 June to 1 August 2022 were tested for MPXV, and whole-genome sequencing (WGS) was performed on two strains. Ten cases were identified: eight were young adult males, including six MSMs, and two were female. Nine subjects reported recent sexual exposure. One female subject without sexual exposure only reported attendance at a social gathering. Overall, 7 of 10 skin lesion samples had a high viral load of MPXV DNA, and 6/9 whole blood samples and 6/8 nasopharyngeal swab samples also tested positive. The analyzed sequences belonged to Clade 3, lineage B.1, and B.1.5, respectively. Despite this recent multinational outbreak of MPXV cases having revealed a high proportion of cases occurring among MSM, the identification of cases among heterosexual subjects and in a female subject without sexual risk factors should raise awareness among clinicians about the possible spread of MPXV in the general population.

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Section: Discussionmentioning

confidence: 99%

Monkeypox Virus Infections in Southern Italy: Is There a Risk for Community Spread?

Loconsole

Sallustio

Centrone

et al. 2022

IJERPH

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“…The basic reproductive number (R0) was higher than 1 in MSM (Men who have Sex with Men) populations and lower than 1 in other populations, as estimated by mathematical models. R0 was estimated to be 1.8 in Spain, 1.6 in the UK, and 1.4 in Portugal ( 18 ). At present, there were no confirmed human monkeypox patients in mainland China in 2022, which may be due to the government's strict new crown entry quarantine measures and the active promotion of human monkeypox prevention and control knowledge to the public.…”

Section: Discussionmentioning

confidence: 99%

Bibliometric analysis of human monkeypox research from 1975 to 2022 and novel prevention and control strategies

Lin

Zhong

et al. 2022

Front. Public Health

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BackgroundSince human monkeypox was reported, many related literatures have been published. This study aimed to evaluate the research hotspots and future development trends of human monkeypox by a bibliometric analysis, to analyze the preventive and control measures of various countries in response to human monkeypox outbreaks.MethodsThe Web of Science Core Collection database was searched for all monkeypox related literature published from 1975 to 2022, and the search strategy was “TS = monkeypox.” Bibliometric analysis was performed using VOSviewer software based on retrieval data. Contribution metric methods and visualization were used to analyze the top issues in the field of human monkeypox.ResultsFrom 1975 to 2022, a total of 1,068 monkeypox research papers were included, of which American researchers published 663 papers, and it was also the country that participated in the most international cooperation. Centers for Disease Control Prevention USA is the most prolific institution and a leader in research collaborations. The Journal of Virology has the largest number of published papers on monkeypox. In addition, Damon Inger K has made significant contributions to monkeypox research, with both the most published and the most citation. A total of 2,847 keywords were identified, four top topics were obtained through cluster analysis: (1) human monkeypox epidemiology and species research. (2) human monkeypox virus vaccine and experimental research. (3) human monkeypox disease diagnosis and treatment studies. (4) human monkeypox disease prevention and immunization studies. To curb the spread, regions or countries have developed and implemented detailed managements. The prevention and control measures focus on the isolation of suspected or confirmed patients, the investigation and tracking of the source of the disease, the disposal of pollutants, vaccination and the protection of health workers.ConclusionsThe number of human monkeypox literature has grown since 2003. Infection, vaccine and efficacy were the top topic over the past 47 years while the contact tracing, testing, surveillance and vaccination have been the major concerns since the human monkeypox outbreak in May 2022. The treatment and management of human monkeypox deserves further attention.

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“…Immunodeficiency may lead to worse clinical outcomes of a monkeypox infection (10). Liu et al (11) suggested that an advanced or poorly virally controlled HIV infection may lead to more severe outcomes after monkeypox infection. According to Thornhill et al…”

Section: Vaccine Stockpile and Vaccinationmentioning

confidence: 99%

Monkeypox – A danger approaching Asia

Liu

Zhu

Miao

et al. 2022

BST

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Monkeypox, a zoonotic disease, was first identified in humans in the Democratic Republic of the Congo in 1970. In the 50 years since its inception, the monkeypox endemic was concentrated in Central and West Africa. Sporadic cases reported in Europe and North America were linked to imported cases (1). On May 7, 2022, a confirmed case of monkeypox was first reported in the United Kingdom, and several countries subsequently reported cases of monkeypox, spanning the globe from Europe to North America, Africa, and Asia. Since the end of June 2022, cases have tended to sharply increase globally (2). Given the risk of this epidemic spreading, the WHO declared the monkeypox epidemic a global public health emergency, which is the WHO's highest level of public health alert (Figure 1).

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Monkeypox claims new victims: the outbreak in men who have sex with men

Cited by 56 publications

References 7 publications

Monkeypox Virus Infections in Southern Italy: Is There a Risk for Community Spread?

Monkeypox Virus Infections in Southern Italy: Is There a Risk for Community Spread?

Bibliometric analysis of human monkeypox research from 1975 to 2022 and novel prevention and control strategies

Monkeypox – A danger approaching Asia

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