Monkeypox infection and bacterial cellulitis: a complication to look for

Sousa, Diogo de; Frade, Joana Vieitez; Patrocínio, João; Borges‐Costa, João; Filipe, Paulo

doi:10.1016/j.ijid.2022.08.024

Cited by 19 publications

(12 citation statements)

References 11 publications

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“…We assessed the eligibility of the remaining 1349 studies by reading full-text papers: 1112 did not report clinical features and epidemiological characteristics of mpox; one reported duplicated cases (the one with more detailed information was included), and three reported cases before 6 May 2022 (cases confirmed in 2017–2021), one reported asymptomatic cases. Seventy-seven studies [ 4 , 8 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 ,…”

Section: Resultsmentioning

confidence: 99%

“…Seventy-seven studies [ 4 , 8 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , …”

Section: Resultsunclassified

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Clinical Characteristics of Human Mpox (Monkeypox) in 2022: A Systematic Review and Meta-Analysis

Liu

Wang

et al. 2023

Pathogens

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Since May 2022, large numbers of monkeypox (mpox) cases have been reported in non-endemic regions. We conducted a systematic review and meta-analysis to elucidate clinical characteristics of the current mpox outbreak. Our systematic review and meta-analysis were undertaken according to PRISMA and MOOSE guidelines. We searched PubMed, EMBASE, and Web of Science for publications between 1 January and 11 November 2022. Random-effects models were used to pool results. Heterogeneity was assessed using I2. This study is registered with PROSPERO, CRD42022355590. Skin lesions (95.2%, 95% CI [93.3–96.9%]), fever (58.4%, [54.9–61.8%]) and lymphadenopathy (53.0%, [48.7–57.3%]) were the most common symptoms. The most common dermatological manifestations were anogenital lesions (65.7%, [57.8–73.0%]), and the most common lymphadenopathy was inguinal (46.8%, [40.6–53.0%]). There were no differences in symptoms including malaise, fever, headache, and genital, anal, and oropharyngeal lesions according to HIV infection status. Median age of patients varied from 15 to 57.5 years (median, 35 years). The median proportion of men who had sex with men (MSM) was 100.0% (20.6–100.0%). The median proportion of patients who reported recent sexual exposure was 99.2% (14.3–100.0%). The median proportion of PLHIV was 42.2% (0.0–100.0%). Skin lesions, fever, inguinal lymphadenopathy, and anogenital lesions were the most common symptoms of mpox reported in the current outbreak. Existing guidelines should be updated to reflect these clinical manifestations and groups at highest risk of infection, MSM in particular.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsunclassified

Clinical Characteristics of Human Mpox (Monkeypox) in 2022: A Systematic Review and Meta-Analysis

Liu

Wang

et al. 2023

Pathogens

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“…The natural progression of the skin lesions with ulceration might create a portal of entry for bacterial skin infections. 8 In our case, we prescribed topical acid fusidic cream as prophylaxis.…”

Section: Oro-mammary Inoculation Pathway Of Monkeypox In a Female Pat...mentioning

confidence: 86%

Oro‐mammary inoculation pathway of monkeypox in a female patient

Mancha

Brazão

Filipe

2022

Acad Dermatol Venereol

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“…Infrequently, complications such as encephalitis, pneumonitis, digestive involvement, ocular diseases leading to loss of visual acuity, kidney injury, skin and soft tissue infections and abscesses may occur over the first 5–28 days of illness ( Figure 1 ) [ 50 , 86 , 87 ]. Another rare occurrence is the myopericarditis directly due to the virus or through immune-mediated injury [ 88 ].…”

Section: Pathophysiology and Clinical Featuresmentioning

confidence: 99%

Human Monkeypox—A Global Public Health Emergency

Zardi

Chello

2022

IJERPH

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Monkeypox, a viral zoonosis caused by an Orthopoxvirus, is clinically characterized by fever, headache, lymphadenopathy, myalgia, rash and burdened by some complications that can be severe and life threatening. Monkeypox, endemic in some central and west African countries, in tropical areas near equator, rose to the headlines following its recent outbreak in non-endemic countries of Europe and the USA. Thus, the World Health Organization, worried about the growing dimension of the problem, declared monkeypox a global public health emergency. Now, after months of careful observation, the western scientific research is drawing conclusion that African endemic countries represent a reserve pool able to feed, through travelers and sexual networks, the outbreak in non-endemic countries in which high-risk communities such as gay and bisexual men are the most affected. Prevention through vaccination and early diagnosis are the core to breaking the chain of diffusion of this epidemic. Particular attention should be paid to avoid the spread from endemic countries, also implementing the economic investments in their public health system. Information campaigns and assistance to high-risk classes in non-endemic countries are important priorities, however, assuming that specific treatments for this disease are still tentative.

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Monkeypox infection and bacterial cellulitis: a complication to look for

Cited by 19 publications

References 11 publications

Clinical Characteristics of Human Mpox (Monkeypox) in 2022: A Systematic Review and Meta-Analysis

Clinical Characteristics of Human Mpox (Monkeypox) in 2022: A Systematic Review and Meta-Analysis

Oro‐mammary inoculation pathway of monkeypox in a female patient

Human Monkeypox—A Global Public Health Emergency

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