Monolithic CMOS ISFET with Built-in Gold Reference Electrode and Readout Circuit with Frequency-adjustable Pulse Output in Bio Detection

A biosensor for the direct determination of organophosphorus pesticides (OPs) is described. It utilizes an ion‐selective field‐effect transistor and phosphotriesterase enzyme (PTE), which provides cleavage of OPs. The sensitivity of the biosensor was increased after PTE immobilization on the surface of the transistor. Packaging of the integrated circuit and creation of a microfluidic system for analyte delivery stabilized the signal. This system was able to detect 0.1 µM paraoxon and 0.5 µM parathion and methyl parathion and was stable for at least 1 month (PBS, 1°), and could thus provide the basis for a portable device for analyzing OPs in water.

show abstract

Development of a Biosensor Based on Phosphotriesterase and n‐Channel ISFET for Detection of Pesticides

Andrianova

Gubanova

Комарова

et al. 2016

Electroanalysis

View full text Add to dashboard Cite

show abstract

Improved Sensitivity and Stability for SnO Ion-Sensitive Field-Effect Transistor-Based pH Sensor by Electrical Double Layer Gate and AlO Sensitive Film

Yang

et al. 2022

IEEE Trans. Electron Devices

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Monolithic CMOS ISFET with Built-in Gold Reference Electrode and Readout Circuit with Frequency-adjustable Pulse Output in Bio Detection

Cited by 2 publications

References 8 publications

Development of a Biosensor Based on Phosphotriesterase and n‐Channel ISFET for Detection of Pesticides

Development of a Biosensor Based on Phosphotriesterase and n‐Channel ISFET for Detection of Pesticides

Improved Sensitivity and Stability for SnO Ion-Sensitive Field-Effect Transistor-Based pH Sensor by Electrical Double Layer Gate and AlO Sensitive Film

Contact Info

Product

Resources

About