Mononuclear transition metal complexes with sterically hindered carboxylate ligands: Synthesis, structural and spectral properties

New Bioactive Heteroleptic Copper(II) Carboxylates: Structure, Enzymatic and DNA-Binding Studies

“…The striking application of metal carboxylates is that they act as accelerators for a number of industrially and biologically important chemical reactions such as oxidations, reductions, couplings, C-H insertions, transformations, and charge transfers. [1][2][3][4] A number of bioactive metal carboxylates have also been reported to date. 5,6 Inevitable relationship between chemical reactions naturally carried out within the human body, pharmacology and medicine has lead the scientists to design new bioactive materials in the form of potent drugs for therapeutic intervention in treatment of many life threatening diseases.…”

Bis(4,4′′-difluoro-1,1′:3′,1′′-terphenyl-2′-carboxylato-κO)bis(3,5-dimethyl-1H-pyrazole-κN2)manganese(II)

“…The synthesis of terphenyl-based carboxylate ligands has been reported (Saednya et al, 1996;Du et al, 1986;Chen et al, 1994). Also four coordinate Fe 2+ , Co 2+ , and Ni 2+ metal complexes with a slightly distorted tetrahedral coordination geometry have also been reported with two 3,5-dimethylpyrazole and two 4,4′′-difluoro-[1,1′:3′,1′′-terphenyl]-2′-carboxylato ligands (Kannan et al 2011;Yoon & Lippard, 2004a). Complexes with 3,5-dimethylpyrazole ligands have also been reported (Zhang et al, 2007;Cheng et al, 1990).…”

Bis(μ-4,4′′-difluoro-1,1′:3′,1′′-terphenyl-2′-carboxylato-κ2O:O′)bis[aqua(4,4′′-difluoro-1,1′:3′,1′′-terphenyl-2′-carboxylato-κO)(pyridine-κN)cobalt(II)] diethyl ether disolvate

“…For background to metal complexes with 4,4 00 -difluoro-1,1 0 :3 0 ,1 00 -terphenyl-2 0 -carboxylate ligands, see: Kannan et al (2011) and to water-bridged di-cobalt complexes, see: Lee et al (2002). Bimetal systems, ligated by four carboxylates and two histidines derived from the side chains of amino acids, are often found in metalloenzyme active sites, see: Holm et al (1996); Lippard & Berg (1994).…”