Monophasic Synovial Sarcoma of Prostatic Fascia: Case Report and Literature Review

Abstract

Synovial sarcoma (SS) primarily occurs in the para-articular soft tissue of the lower extremities in young adults and it is extremely rare in the prostatic region. We report a case of a 46-year-old man who presented with urinary retention. Pelvic ultrasound (US) examination, computed tomography (CT), and magnetic resonance imaging (MRI) demonstrated an 8.5 cm mass that appeared to originate in the prostatic fascia of the right lobe. Preoperative prostatic ultrasound transrectal needle biopsy revealed mesenchymal neoplastic tissue. Patient underwent surgery. The final pathologic findings were consistent with the diagnosis of monophasic synovial sarcoma.

Primary prostate synovial sarcoma: A case report and review of literature

“…The earliest case of SS of the prostate was reported by Iwasaki et al in 1999 in the American Journal of Surgical Pathology [1]. Through a literature search, we found that nine cases of prostate SS were clearly diagnosed by molecular studies in the English literature [1] , [2] , [3] , [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] . Together with our report, there were a total of 10 cases.…”

“…Prostate comply SS is extremely rare in clinical practice. The first case was reported by Iwasaki et al in 1999 [1] , and we retrieved nine cases in the English literature that were confirmed as primary SS of the prostate by molecular detection methods [1] , [2] , [3] , [4] , [5] , [6] , [7] , [8] , [9] , [10] . In the prostate biopsy, a case of prostate SS was found, which was confirmed to be prostate SS by immunohistochemistry and fluorescence in situ hybridization (FISH).…”

18F-FDG PET/CT Findings in a Patient With Primary Prostatic Synovial Sarcoma Combined With Adrenocortical Carcinoma

“…5 Although in this case, no evidences of metastases were found. The radiological features of primary prostatic synovial sarcoma are not characteristic, which may present large hypoechoic lesion on ultrasound and soft tissue tumor with mixed cystic/solid components on CT. 2,5 The adrenocortical carcinoma is an aggressive tumor with poor 5-year survival rate, 6 and the majority of adrenocortical carcinoma, like this case, show hypermetabolism on 18 F-FDG PET/CT. 7,8 Here, we present a rare case of primary prostatic synovial sarcoma and combined adrenocortical carcinoma.…”

Primary Prostatic Synovial Sarcoma With Pulmonary Metastases Identified by Routine Next-Generation Sequencing

“…In the time since Iwasaki and colleagues described the first known case of primary prostatic synovial sarcoma in 1999, only 11 total cases have been reported in the English literature to date. [7][8][9][10][11][12][13][14][15][16] We herein present what we believe is the 12th reported case of primary prostate synovial sarcoma on the basis of the published literature, and to our knowledge is only the second reported case of primary synovial sarcoma of the prostate with pulmonary metastatic disease at presentation.…”