Monte Carlo Inverse Folding

Abstract

The RNA Inverse Folding problem comes from computational biology. The goal is to find a molecule that has a given folding. It is important for scientific fields such as bioengineering, pharmaceutical research, biochemistry, synthetic biology and RNA nanostructures. Nested Monte Carlo Search has given excellent results for this problem. We propose to adapt and evaluate different Monte Carlo Search algorithms for the RNA Inverse Folding problem.