2022
DOI: 10.3389/fcvm.2022.871967
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Monte Carlo Simulation and Reconstruction: Assessment of Myocardial Perfusion Imaging of Tracer Dynamics With Cardiac Motion Due to Deformation and Respiration Using Gamma Camera With Continuous Acquisition

Abstract: PurposeMyocardial perfusion imaging (MPI) with single photon emission computed tomography (SPECT) is routinely used for stress testing in nuclear medicine. Recently, our group extended its potential going from 3D visual qualitative image analysis to 4D spatiotemporal reconstruction of dynamically acquired data to capture the time variation of the radiotracer concentration and the estimated myocardial blood flow (MBF) and coronary flow reserve (CFR). However, the quality of reconstructed image is compromised du… Show more

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“…Könik et al ( 30 ) preliminarily evaluated the impact of different angular views on MPH SPECT imaging, while this study provided a more thorough investigation for different pinhole and projection numbers and evaluated the effect of detector positions of a conventional dual-head SPECT system for a limited number of projections. Though a full ring system is expected to provide the best dynamic SPECT performance, Huh et al ( 45 ) proposed a 4D spatiotemporal reconstruction method for dynamic sequences of separate respiratory and cardiac phases, utilizing a conventional dual-head SPECT camera with detector rotations. Fewer angular views which lead to fewer detector movements may be advantageous for potential dynamic brain acquisition.…”
Section: Discussionmentioning
confidence: 99%
“…Könik et al ( 30 ) preliminarily evaluated the impact of different angular views on MPH SPECT imaging, while this study provided a more thorough investigation for different pinhole and projection numbers and evaluated the effect of detector positions of a conventional dual-head SPECT system for a limited number of projections. Though a full ring system is expected to provide the best dynamic SPECT performance, Huh et al ( 45 ) proposed a 4D spatiotemporal reconstruction method for dynamic sequences of separate respiratory and cardiac phases, utilizing a conventional dual-head SPECT camera with detector rotations. Fewer angular views which lead to fewer detector movements may be advantageous for potential dynamic brain acquisition.…”
Section: Discussionmentioning
confidence: 99%