Montmorillonite K10 catalyzed efficient synthesis of amidoalkyl naphthols under solvent free conditions

Sodium hydrogen sulfate as effective and reusable heterogeneous catalyst for the one-pot preparation of amidoalkyl naphthols

“…Yields refer to the pure isolated products. All known products have been reported previously in the literature and were characterized by comparison of IR and NMR spectra with authentic samples [15][16][17][18][19][20][21][22]. Method A: the reaction was carried out with 45mg of NaHSO 4 As shown in Table 1, the three-component reaction of 2-naphthol, arylaldehydes, and acetonitrile (reactant as well as solvent, 5 mL) or acetamide was performed in the presence of sodium hydrogen sulfate (45 mg).…”

“…The desired pure product(s) was characterized by comparison of their physical data with those of known compounds. [15][16][17][18][19][20] The spectral data of the new amidoalkyl naphthols are given below. …”

An Efficient and Green Protocol for the Synthesis of Dihydropyrano [2,3-C] Pyrazoles in Aqueous Medium Using Thiamine Hydrochloride as a Catalyst

“…From the ecofriendly point of view combining with economic aspects "Green chemistry" emphasizes the development of metal ion free, environmentally safe and convenient reagents in the MCRs 20 . In this regard, thiamine hydrochloride (VB 1 ; Fig.…”

Incredible Role of Glycerol in Multicomponent Synthesis of 2,3-Dihydroquinazoline-4(1H)-ones and 1-Amidoalkyl-2-naphthols

“…5 Also 2,3-Dihydroquinazolinone derivatives are an important class of fused heterocycles that display a wide range of biological, pharmacological, and medicinal properties involving antitumor, antibiotic, antipyretic, analgesic, antihypertonic, diuretic, antihistamine, antidepressant, and vasodilating activities. 6 The preparation of 1-amidoalkyl-2-naphthols can be carried out by the condensation of aryl aldehydes, 2-naphthol and acetonitrile or amide in the presence of Lewis or Brønsted acid catalysts 7 such as K-10 clay, 8 Ce(SO4)2, 9 iodine, 10 K5CoW12O40• 3H2O, 11 p-TSA, 12 sulfamic acid, 13 cation-exchanged resins, 14 silica-sulfuric acid, 15 silica supported dual acidic ionic liquid,…”