Moral judgment in patients with idiopathic generalized epilepsy

Jiang, Yubao; Zhu, Yi-Ming; Wu, JiaoNan; Zhang, Nong; Hu, Panpan; Wang, Kai

doi:10.1016/j.seizure.2016.08.002

Cited by 4 publications

(3 citation statements)

References 34 publications

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“…When compared with healthy controls, individuals with temporal lobe epilepsy have not shown impaired sensitivity to moral and conventional rules (Giovagnoli et al, 2021), but individuals with generalized epilepsy with impaired frontal lobe function were found to choose more utilitarian options than healthy controls in impersonal dilemmas, suggesting an effect of impaired frontal function on moral reasoning (Jiang et al, 2016). In sum, altered moral behavior can be associated with epilepsy, but it is most frequently associated with any underlying brain disease or concomitant factors, including frontal-executive dysfunction.…”

Section: Brain Diseases With Potential Moral Violationsmentioning

confidence: 99%

The Implications of Moral Neuroscience for Brain Disease: Review and Update

Mendez

2023

Cognitive and Behavioral Neurology

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The last 2 decades have seen an explosion of neuroscience research on morality, with significant implications for brain disease. Many studies have proposed a neuromorality based on intuitive sentiments or emotions aimed at maintaining collaborative social groups. These moral emotions are normative, deontological, and action based, with a rapid evaluation of intentionality. The neuromoral circuitry interacts with the basic mechanisms of socioemotional cognition, including social perception, behavioral control, theory of mind, and social emotions such as empathy. Moral transgressions may result from primary disorders of moral intuitions, or they may be secondary moral impairments from disturbances in these other socioemotional cognitive mechanisms. The proposed neuromoral system for moral intuitions has its major hub in the ventromedial prefrontal cortex and engages other frontal regions as well as the anterior insulae, anterior temporal lobe structures, and right temporoparietal junction and adjacent posterior superior temporal sulcus. Brain diseases that affect these regions, such as behavioral variant frontotemporal dementia, may result in primary disturbances of moral behavior, including criminal behavior. Individuals with focal brain tumors and other lesions in the right temporal and medial frontal regions have committed moral violations. These transgressions can have social and legal consequences for the individuals and require increased awareness of neuromoral disturbances among such individuals with brain diseases.

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Section: Brain Diseases With Potential Moral Violationsmentioning

confidence: 99%

The Implications of Moral Neuroscience for Brain Disease: Review and Update

Mendez

2023

Cognitive and Behavioral Neurology

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“…There has also been an attempt to shed light on the connection between affective processes and responses to moral dilemmas in the context of various clinical populations (de Achával et al, 2013;Gago et al, 2019;Gleichgerrcht, Tomashitis, & Sinay, 2015;Gleichgerrcht et al, 2013;Jiang et al, 2016;Kim et al, 2015;Larsen et al, 2019;McGuire, Brüne, & Langdon, 2017;Patil, Melsbach, Hennig-Fast, & Silani, 2016). Of relevance to the current investigation is the diagnostic class known as anxiety disorders (which includes social anxiety disorder, panic disorder, specific phobias, agoraphobia, generalized anxiety disorder, and until the recent change to the classification system, obsessive-compulsive disorder and PTSD).…”

Section: Moral Cognition About Harm In Anxiety Disordersmentioning

confidence: 99%

Moral Cognition About Harm in Anxiety Disorders: The Importance of Experienced Emotion

et al. 2020

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Recent work has shown that emotional arousal influences decision-making in sacrificial moral dilemmas, with heightened levels of arousal associated with increased aversion to committing moral transgressions to maximize utilitarian outcomes. Patients with anxiety disorders experience pathologically heightened states of arousal and thus may be expected to exhibit reduced utilitarian responding on such dilemmas. Extant evidence has been mixed, however, regarding whether anxious patients differ in their moral decisions from controls, and no study has conducted a careful examination of emotions experienced during decision-making. We administered sacrificial moral dilemmas to a cohort of 95 patients from across the spectrum of anxiety disorders to test whether they differed from matched controls on a) utilitarian decision-making, and b) ratings of experienced emotion during the moral deliberative process. Results showed no group differences between patients and controls on endorsement of utilitarian sacrificial action or on reported experience of emotionality during the experiment. Additionally, exploratory analysis revealed that specific emotions were correlated with utilitarian judgments. These results are in line with the Dual Process Theory model’s prediction that decreased utilitarian responding will be concomitant with an increased emotional arousal. Our findings support past work indicating that moral cognition is intact in anxiety disorders despite the emotional dysregulation characteristic of anxious psychopathology. Future work would benefit from the use of process-dissociation techniques to further clarify whether emotional or cognitive processes may differ in anxiety disorders during moral cognition.

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“…A análise volumétrica representa um dos aspectos estudados quando se pretende avaliar a morfometria encefálica, além do estudo da superfície cortical e da espessura cortical (Loughman et al, 2014;Jiang et al, 2016).…”

Section: Aspectos De Dti Nas Egisunclassified

Epilepsias generalizadas idiopáticas: fatores clínicos e de neuroimagem relacionados ao difícil controle medicamentoso

Lobato¹

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Moral judgment in patients with idiopathic generalized epilepsy

Cited by 4 publications

References 34 publications

The Implications of Moral Neuroscience for Brain Disease: Review and Update

The Implications of Moral Neuroscience for Brain Disease: Review and Update

Moral Cognition About Harm in Anxiety Disorders: The Importance of Experienced Emotion

Epilepsias generalizadas idiopáticas: fatores clínicos e de neuroimagem relacionados ao difícil controle medicamentoso

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