Morbidity in relation to the clinical forms and to intensity of infection in<i>Schistosoma mansoni</i>infections in the Sudan

Salih, S Y; Marshall, T. F. de C.; Radalowicz, A

doi:10.1080/00034983.1979.11687283

Cited by 9 publications

(7 citation statements)

References 8 publications

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“…Some studies suggest an inverse relationship between the degree of infection caused by S. mansoni and concentrations of hemoglobin. 8,22 However, in studies involving schoolchildren, significant reductions in the concentration of hemoglobin related to the increase in the degree of infection were not observed. 23 Friis and others, 24 also studying schoolchildren, showed that intensity of S. mansoni infection was not predictive of ferritin concentrations.…”

Section: Discussionmentioning

confidence: 99%

Moderate- And Low-Intensity Co-Infections by Intestinal Helminths and Schistosoma Mansoni, Dietary Iron Intake, and Anemia in Brazilian Children

Brito¹,

Barreto²,

Silva³

et al. 2006

The American Journal of Tropical Medicine and Hygiene

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Abstract. To determine the role of moderate-and low-intensity infections with Schistosoma mansoni and intestinal helminths (hookworm, Trichuris trichiura, Ascaris lumbricoides) on the prevalence of anemia and their relationship to iron consumption, a cross-section of 1,709 children in rural Brazil was studied. All participants were selected for infection with one or multiple helminthic parasites, and demographic, anthropometric, and dietary intake were surveyed. The prevalence and intensity were as follows: hookworm infection, 15.7% and 8.6 eggs/g; T. trichiura, 74.8% and 190.5 eggs/g; A. lumbricoides, 63% and 1,905.5 eggs/g; S. mansoni, 44.5% and 60.3 eggs/g. There was no increase in odds ratio for anemia with any combination of intestinal helminths without S. mansoni infection. By logistic regression, the odds ratio for having anemia when infected with S. mansoni and two intestinal helminths was 1.7 (95% CI, 1.1-2.5) and for S. mansoni and three intestinal helminths was 2.4 (95% CI, 1.2-4.6) compared with children with a single parasite species. Children with an adequate intake of iron had no increased odds of anemia independent of the combination of parasite infections.

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Section: Discussionmentioning

confidence: 99%

Moderate- And Low-Intensity Co-Infections by Intestinal Helminths and Schistosoma Mansoni, Dietary Iron Intake, and Anemia in Brazilian Children

Brito¹,

Barreto²,

Silva³

et al. 2006

The American Journal of Tropical Medicine and Hygiene

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“…With lifelong exposure, hepatomegaly and/or splenomegaly peaks in the 2 nd -3 rd decade of life along with symptoms of bloody stools and colicky abdominal pain [138, 139]. Varices can develop but cirrhosis is not seen [165].…”

Section: Eosinophilia In Indigenous Population (Immigrant/refugeementioning

confidence: 99%

“…Varices can develop but cirrhosis is not seen [165]. Mild eosinophilia (<1000/μL) is seen in approximately 50% of patients [139]. …”

Section: Eosinophilia In Indigenous Population (Immigrant/refugeementioning

confidence: 99%

Eosinophilia in Infectious Diseases

O’Connell

Nutman

2015

Immunology and Allergy Clinics of North America

107

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“…Combined infections with S. mansoni and S. haematobium have also been reported to contribute to greater anaemia among heavy vs . light infections (Salih, Marshall and Radalowicz, 1979).…”

Section: Anaemia Profilesmentioning

confidence: 99%

“…Likewise, heavy S. haematobium infection has been reported to be significantly associated with lower Hb levels relative to light infection status (King et al 2005). Combined infections with S. mansoni and S. haematobium have also been reported to contribute to greater anaemia among heavy vs. light infections (Salih, Marshall and Radalowicz, 1979).…”

Section: U L T R a S O N O G R A P H Ymentioning

confidence: 99%

Evaluation and application of potential schistosome-associated morbidity markers within large-scale mass chemotherapy programmes

et al. 2009

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A primary objective of schistosomiasis control programmes is to achieve, and hence also demonstrate, a quantifiable reduction in schistosome-associated morbidity as a consequence of chemotherapeutic intervention. Inherent within such an objective, it is necessary to define and validate direct and indirect indicators of schistosome-related morbidity. However, to define and thereby document such morbidity, and its reduction following treatment, may not be straightforward, particularly for intestinal schistosomiasis-induced morbidity, which is often not apparent in all but the most severe or chronic cases. Within all 'Schistosomiasis Control Initiative' activities, across selected sub-Saharan African countries since 2002, a range of standard and novel potential morbidity markers have been monitored and evaluated. Parasitological intensity measures, combined with haemoglobin/anaemia counts and ultrasonography, proved valuable schistosomiasis-related morbidity indicators, being both logistically practical and informative. Additional measures tested, such as albumin excretion profiles, were promising, and are subject to ongoing research, whilst some measures, such as distended stomach/umbilical circumference, anthropometrics and health questionnaires proved less reliable. These results serve to both illustrate the success of current control activities in reducing schistosome-induced morbidity, and to highlight key tools and techniques for continued application within ongoing and future mass drug administration programmes.

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Morbidity in relation to the clinical forms and to intensity of infection inSchistosoma mansoniinfections in the Sudan

Cited by 9 publications

References 8 publications

Moderate- And Low-Intensity Co-Infections by Intestinal Helminths and Schistosoma Mansoni, Dietary Iron Intake, and Anemia in Brazilian Children

Moderate- And Low-Intensity Co-Infections by Intestinal Helminths and Schistosoma Mansoni, Dietary Iron Intake, and Anemia in Brazilian Children

Eosinophilia in Infectious Diseases

Evaluation and application of potential schistosome-associated morbidity markers within large-scale mass chemotherapy programmes

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